Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | DBH | P09172 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765980 | 0.88 | DRD2 (0.50) | ACHEALDH1A1HTTGRM2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL26124950 | 0.87 | DRD2 (0.49) | ACHEALDH1A1HTTGRM2SIGMAR1 | |
| SCHEMBL3144826 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HTTGRM2SIGMAR1DPP4 | |
| Hydrochloric Acid SCHEMBL4033471 | 0.84 | ALDH1A1 (0.63) | ALDH1A1HTTGRM2SIGMAR1DPP4 | |
| SCHEMBL8151034 | 0.82 | ALDH1A1 (0.49) | ACHEALDH1A1HTTGRM2SIGMAR1 | |
| SCHEMBL4033714 | 0.82 | SIGMAR1 (0.51) | ALDH1A1HTTSIGMAR1KDM4E | |
| SCHEMBL4694589 | 0.81 | ALDH1A1 (0.72) | ACHEALDH1A1HTTKDM4E | |
| SCHEMBL8140940 | 0.79 | JAK2 (0.48) | ALDH1A1HTTGRM2SIGMAR1 | |
| SCHEMBL2821325 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HTTGRM2SIGMAR1KDM4E | |
| SCHEMBL3150518 | 0.79 | SOS1 (0.55) | ALDH1A1HTTSIGMAR1KDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053911-A1 | ADIPONECTIN RECEPTOR-ACTIVATING COMPOUND | The University of Tokyo (JP) | 2016-08-10 | — | — | EP | disclosed |