SCHEMBL17994124

SCHEMBL17994124

FC(F)(F)C1CC(I)CN1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31203667 0.70 PNMT (0.41) PNMT
SCHEMBL17951179 0.70 PNMT (0.41) PNMT
SCHEMBL7315446 0.65 L3MBTL1 (0.39) PNMT
SCHEMBL21957487 0.61 CHRM2 (0.31) PNMT
SCHEMBL8829065 0.60 PNMT (0.33) PNMT
SCHEMBL14919273 0.60 PNMT (0.33) PNMT
SCHEMBL25845723 0.60
SCHEMBL21360180 0.60
SCHEMBL23938156 0.59 PNMT (0.36) PNMT
SCHEMBL25025774 0.59 PNMT (0.32) PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3053926-A1 FUSED PYRIMIDINE COMPOUND, INTERMEDIATE, PREPARATION METHOD THEREFOR, AND COMPOSITION AND APPLICATION THEREOF Shanghai Yingli Pharmaceutical Co. Ltd. (CN) 2016-08-10 EP disclosed