SCHEMBL7315446

SCHEMBL7315446

FC(F)(F)C1CC2CCCCC2CN1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
PNMT P11086 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9569703 0.70
SCHEMBL5178366 0.69
SCHEMBL25635357 0.68 L3MBTL1 (0.37) L3MBTL1
SCHEMBL9569674 0.65
SCHEMBL14609252 0.65 L3MBTL1 (0.42) L3MBTL1
SCHEMBL17951179 0.65 PNMT (0.41) PNMT
Hydrochloric Acid SCHEMBL31203667 0.65 PNMT (0.41) PNMT
SCHEMBL17994124 0.65 PNMT (0.41) PNMT
SCHEMBL12333939 0.65 L3MBTL1 (0.42) L3MBTL1PNMT
SCHEMBL8796560 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5605926-A PROPHYLAXIS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-25 US disclosed
US-5430151-A Treatment of aids, pneumonia, caprine arthritis encephalitis, leukemia and immmunodeficiency BAYER AKTIENGESELLSCHAFT (DE) 1995-07-04 US disclosed
US-5204471-A α-trifluoromethyl-substituted, saturated bicyclic amines BAYER AKTIENGESELLSCHAFT (DE) 1993-04-20 US disclosed
EP-0528242-A2 Trifluoromethyl containing pseudopeptides BAYER AG (DE) 1993-02-24 EP disclosed
EP-0527385-A1 Alpha-trifluoromethyl substituted, saturated bicyclic amines and process for their preparation BAYER AG (DE) 1993-02-17 EP disclosed