Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.44 |
| ▸ | ACE | P12821 | 5/20 | 0.44 |
| ▸ | MME | P08473 | 4/20 | 0.44 |
| ▸ | CPA1 | P15085 | 4/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834638 | 0.90 | ITGB1 (0.40) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL17834635 | 0.84 | ITGB1 (0.40) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL17834643 | 0.83 | ITGB1 (0.40) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL17834669 | 0.83 | DGAT1 (0.41) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL22448951 | 0.82 | PTPN1 (0.46) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL22449248 | 0.82 | PTPN1 (0.46) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL15037196 | 0.82 | PTPN1 (0.46) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL15037313 | 0.82 | PTPN1 (0.46) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL17834624 | 0.82 | L3MBTL1 (0.41) | ITGB1ITGA4ACEMMECPA1 | |
| SCHEMBL17995135 | 0.82 | CA2 (0.46) | ITGB1ITGA4PTPN1BCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160228450-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | ITGB1 3589/4885ITGA4 4651/4885ACE 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.