Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17995479 | 0.94 | TSHR (0.41) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL1474193 | 0.78 | TSHR (0.43) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL1474192 | 0.78 | TSHR (0.43) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL16797125 | 0.74 | TSHR (0.40) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL14278564 | 0.72 | TSHR (0.37) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL17995472 | 0.70 | TSHR (0.43) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL13974849 | 0.70 | LMNA (0.33) | TSHRLMNA | |
| SCHEMBL17995483 | 0.69 | TSHR (0.36) | TSHRLMNAMAPK1CYP2C9MAPT | |
| SCHEMBL17995482 | 0.68 | LMNA (0.31) | TSHRLMNA | |
| SCHEMBL14498909 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016125782-A1 | NOVEL ALICYCLIC ESTER COMPOUND, (METH)ACRYLIC COPOLYMER, AND FUNCTIONAL RESIN COMPOSITION CONTAINING SAME | 三菱瓦斯化学株式会社 | 2016-08-11 | — | — | WO | disclosed |