SCHEMBL179955

SCHEMBL179955

O=[C]CCCCCN1C(=O)C=CC1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.71
FAAH O00519 6/20 0.71
ALDH1A1 P00352 2/20 0.71
LMNA P02545 2/20 0.71
MAPT P10636 2/20 0.71
NPSR1 Q6W5P4 2/20 0.71
HSP90AA1 P07900 1/20 0.71
TLR9 Q9NR96 1/20 0.71
TP53 P04637 1/20 0.71
PKM P14618 1/20 0.71
HPGD P15428 1/20 0.71
XBP1 P17861 1/20 0.71
MAPK1 P28482 1/20 0.71
HTT P42858 1/20 0.71
RECQL P46063 1/20 0.71
RAB9A P51151 1/20 0.71
SMN1; SMN2 Q16637 1/20 0.71
GPR35 Q9HC97 1/20 0.71
GPR55 Q9Y2T6 1/20 0.71
PTGS1 P23219 7/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18040141 1.00 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19514774 1.00 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19514746 0.98 MGLL (0.70) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL366266 0.91 MGLL (0.65) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL34594 0.87 MGLL (0.56) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL13815841 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL549065 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL5383694 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL20351983 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL818349 0.84 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5818 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043670-B2 Anti-BCMA antibody-drug conjugates and methods of use EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-07-23 US claimed
US-20240239885-A1 ANTIBODY CONJUGATE COMPRISING ANTI-P-CADHERIN ANTIBODY AND USES THEREOF WuXi Biologics Ireland Limited (IE) 2024-07-18 US claimed
WO-2023195805-A9 ITGB2-MEDIATED DRUG DELIVERY SYSTEM 트윈피그바이오랩(주) 2024-07-11 WO claimed
EP-4393515-A1 ANTI-CLDN-18.2 ANTIBODY-DRUG CONJUGATE AND USE THEREOF Shanghai Junshi Biosciences Co., Ltd. (CN) 2024-07-03 EP claimed
CN-118076388-A Carrier for targeting beta-D-N-acetylglucosaminidase 国家科学研究中心 2024-05-24 CN claimed
US-20240156978-A1 MAYTANSINE-ANTIBODY CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2024-05-16 US claimed
EP-4366778-A1 ANTIBODY CONJUGATES AND MANUFACTURE THEREOF Bright Peak Therapeutics AG (CH) 2024-05-15 EP claimed
US-20240148888-A1 INTERCELLULAR ADHESION MOLECULE 1 (ICAM1) ANTIBODY DRUG CONJUGATE AND USES THEREOF CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-05-09 US claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
CN-117940169-A Use of antibody drug conjugate and combined drug and use thereof 上海美雅珂生物技术有限责任公司 2024-04-26 CN claimed
WO-2007100385-A2 MACROCYCLIC DEPSIPEPTIDE ANTIBODY-DRUG CONJUGATES AND METHODS GENENTECH, INC. (US) 2007-09-07 WO claimed
EP-1812465-A1 NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES Genentech, Inc. (US) 2007-08-01 EP claimed
EP-1786838-A2 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR GENENTECH, INC. (US) 2007-05-23 EP claimed
EP-1740954-A1 MASS SPECTROMETRY OF ANTIBODY CONJUGATES Kadkhodayan, Miryam (US) 2007-01-10 EP claimed
WO-2006054961-A2 NOVEL COMPOSITION AND METHODS FOR THE TREATMENT OF IMMUNE RELATED DISEASES GENENTECH, INC. (US) 2006-05-26 WO claimed
WO-2006029183-A2 COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR GENENTECH, INC. (US) 2006-03-16 WO claimed
US-20050272118-A1 Novel composition and methods for the treatment of immune related diseases GENENTECH, INC. 2005-12-08 US claimed
WO-2005101017-A1 MASS SPECTROMETRY OF ANTIBODY CONJUGATES GENENTECH, INC. (US) 2005-10-27 WO claimed
US-20050106644-A1 Compositions and methods for the diagnosis and treatment of tumor GENENTECH, INC. 2005-05-19 US claimed
US-20050107595-A1 Compositions and methods for the diagnosis and treatment of tumor GENENTECH, INC. 2005-05-19 US claimed