SCHEMBL366266

SCHEMBL366266

O=[C]CCCN1C(=O)C=CC1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.65
FAAH O00519 6/20 0.65
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62
MAPT P10636 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
HSP90AA1 P07900 1/20 0.62
TLR9 Q9NR96 1/20 0.62
TP53 P04637 1/20 0.62
PKM P14618 1/20 0.62
HPGD P15428 1/20 0.62
XBP1 P17861 1/20 0.62
MAPK1 P28482 1/20 0.62
HTT P42858 1/20 0.62
RECQL P46063 1/20 0.62
RAB9A P51151 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
GPR35 Q9HC97 1/20 0.62
GPR55 Q9Y2T6 1/20 0.62
PTGS1 P23219 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19514746 0.93 MGLL (0.70) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL179955 0.91 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL18040141 0.91 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19514774 0.91 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL34594 0.91 MGLL (0.56) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL797328 0.80 MGLL (0.62) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL155748 0.80 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL331378 0.80 MGLL (0.88) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL258626 0.78 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL5383694 0.78 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN claimed
CN-115244176-A Conjugates of guide RNA-CAS protein complexes 钟明宏 2022-10-25 CN disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US disclosed
US-20220054619-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VIROMETIX AG (CH) 2022-02-24 US disclosed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 CN disclosed
EP-3897708-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES Virometix AG (CH) 2021-10-27 EP disclosed
CN-113260377-A Lipopeptide building blocks and synthetic virus-like particles 维罗米蒂克斯股份公司 2021-08-13 CN disclosed
WO-2020127728-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VIROMETIX AG (CH) 2020-06-25 WO disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 CN disclosed
EP-1603590-A2 INFLUENZA VIRUS VACCINE Merck & Co. Inc. (US) 2005-12-14 EP disclosed
WO-2005003775-A2 GLYCOCONJUGATES AND THEIR USE AS POTENTIAL VACCINES AGAINST INFECTION BY SHIGELLA FLEXNERI INSTITUT PASTEUR (FR) 2005-01-13 WO disclosed
WO-2004080403-A2 INFLUENZA VIRUS VACCINE MERCK & CO. INC. (US) 2004-09-23 WO disclosed
US-20030224992-A1 Transcription factor modulators and uses thereof PRAECIS PHARMACEUTICALS INC. 2003-12-04 US disclosed
WO-2003077931-A1 TRANSCRIPTION FACTOR MODULATORS AND USES THEREOF PRAECIS PHARMACEUTICALS, INC. (US) 2003-09-25 WO disclosed
EP-0726770-A4 SULFAMETHOXAZOLE-SPECIFIC IMMUNOSUPPRESSIVE AGENTS CORTECH INC (US) 1998-02-04 EP disclosed
US-5599912-A DEXTRAN DERIVATIVES WHICH ALSO CONTAIN SULFAMETHOXAZOLE GROUPS, FOR TREATING UNDESIRED IMMUNE RESPONSES TO DRUGS WHICH ALSO CONTAIN THOSE GROUPS CORETECH, INC. (US) 1997-02-04 US disclosed
EP-0726770-A1 SULFAMETHOXAZOLE-SPECIFIC IMMUNOSUPPRESSIVE AGENTS CORTECH, INC. (US) 1996-08-21 EP disclosed
WO-1995007087-A1 SULFAMETHOXAZOLE-SPECIFIC IMMUNOSUPPRESSIVE AGENTS CORTECH, INC. (US) 1995-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 MGLL 539/4885FAAH 2358/4885ALDH1A1 787/4885
US-20220054619-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VSIR, VIP, LRBA MGLL 444/4885FAAH 1579/4885ALDH1A1 4864/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 MGLL 1181/4885FAAH 1494/4885ALDH1A1 1582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.