SCHEMBL34594

SCHEMBL34594

O=[C]CCN1C(=O)C=CC1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.56
FAAH O00519 5/20 0.56
ALDH1A1 P00352 2/20 0.54
LMNA P02545 2/20 0.54
MAPT P10636 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
HSP90AA1 P07900 1/20 0.54
TLR9 Q9NR96 1/20 0.54
TP53 P04637 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
XBP1 P17861 1/20 0.54
MAPK1 P28482 1/20 0.54
HTT P42858 1/20 0.54
RECQL P46063 1/20 0.54
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
GPR35 Q9HC97 1/20 0.54
GPR55 Q9Y2T6 1/20 0.54
PTGS1 P23219 7/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366266 0.91 MGLL (0.65) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19514746 0.89 MGLL (0.70) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL18040141 0.87 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL19514774 0.87 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL179955 0.87 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL3482393 0.78 MGLL (0.54) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL14587456 0.78 MGLL (0.54) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL14678413 0.78 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL145737 0.78 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL2639486 0.76 MGLL (0.50) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2125 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239885-A1 ANTIBODY CONJUGATE COMPRISING ANTI-P-CADHERIN ANTIBODY AND USES THEREOF WuXi Biologics Ireland Limited (IE) 2024-07-18 US claimed
WO-2023195805-A9 ITGB2-MEDIATED DRUG DELIVERY SYSTEM 트윈피그바이오랩(주) 2024-07-11 WO claimed
US-20240156978-A1 MAYTANSINE-ANTIBODY CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2024-05-16 US claimed
WO-2024044550-A1 DLL3 BINDING MOLECULES AND USES THEREOF Abdera Therapeutics Inc. (US) 2024-02-29 WO claimed
EP-4321526-A1 PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF C-Biomex Co., Ltd. (KR) 2024-02-14 EP claimed
US-20240043512-A1 EPITOPES OF ANTI-SERINE PROTEASE INHIBITOR KAZAL (SPIK) ANTIBODIES IMCARE BIOTECH LLC 2024-02-08 US claimed
EP-4313009-A1 MAYTANSINE-ANTIBODY CONJUGATES AND METHODS OF USING SAME Angiex, Inc. (US) 2024-02-07 EP claimed
US-11866496-B2 Humanized anti-CD79B antibodies and immunoconjugates and methods of use GENENTECH, INC. (US) 2024-01-09 US claimed
EP-4294845-A1 IMMUNOCONJUGATES FOR TARGETED RADIOISOTOPE THERAPY Abdera Therapeutics Inc. (US) 2023-12-27 EP claimed
US-11833222-B2 CL and/or CH1 mutated antibodies for drug conjugation LONZA LTD (CH) 2023-12-05 US claimed
WO-2009099728-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2009-08-13 WO claimed
EP-2061814-A2 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR Genentech, Inc. (US) 2009-05-27 EP claimed
US-20090068202-A1 Humanized Anti-CD79B Antibodies and Immunoconjugates and Methods of Use GENENTECH, INC. (US) 2009-03-12 US claimed
EP-2032606-A2 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR Genentech, Inc. (US) 2009-03-11 EP claimed
US-20090028856-A1 Anti-CD79B Antibodies and Immunoconjugates and Methods of Use GENENTECH, INC. (US) 2009-01-29 US claimed
WO-2009012268-A1 ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2009-01-22 WO claimed
WO-2009012256-A1 HUMANIZED ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE GENENTECH, INC. (US) 2009-01-22 WO claimed
WO-2008052187-A2 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH. INC. (US) 2008-05-02 WO claimed
US-20080050310-A1 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH, INC. (US) 2008-02-28 US claimed
WO-2007140371-A2 ANTIBODIES AND IMMUNOCONJUGATES AND USES THEREFOR GENENTECH, INC. (US) 2007-12-06 WO claimed