Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | PIR | O00625 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996448 | 0.94 | LMNA (0.80) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17996450 | 0.86 | LMNA (1.00) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL27986852 | 0.85 | LMNA (0.76) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3149489 | 0.84 | LMNA (0.74) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9633894 | 0.79 | KMT2A (0.73) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17996453 | 0.78 | KMT2A (1.00) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17015171 | 0.78 | KMT2A (1.00) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11132471 | 0.74 | ALDH1A1 (1.00) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| Toluene SCHEMBL7060116 | 0.74 | KMT2A (0.65) | LMNANPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL17996451 | 0.73 | MEN1 (0.63) | LMNANPSR1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229778-A1 | DIRECT B-ARYLATION OF CARBONYL COMPOUNDS | DBH, DDT, CBR3 | LMNA 2375/4885NPSR1 2453/4885KMT2A 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.