Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 5/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470128 | 1.00 | MEN1 (0.37) | MEN1KMT2AMAPK1TSHRPDE10A | |
| SCHEMBL17997013 | 0.91 | — | — | |
| SCHEMBL17564558 | 0.88 | MEN1 (0.44) | MEN1KMT2AMAPK1TSHRPDE10A | |
| SCHEMBL18470127 | 0.88 | MEN1 (0.44) | MEN1KMT2AMAPK1TSHRPDE10A | |
| SCHEMBL13934335 | 0.83 | NCF1 (0.33) | — | |
| SCHEMBL19227229 | 0.80 | MEN1 (0.37) | MEN1KMT2AMAPK1TSHRAPP | |
| SCHEMBL12393233 | 0.79 | TSHR (0.35) | TSHR | |
| SCHEMBL6271267 | 0.78 | ALDH1A1 (0.40) | MAPK1TSHRALDH1A1 | |
| SCHEMBL11136043 | 0.78 | ALDH1A1 (0.40) | MAPK1TSHRALDH1A1 | |
| SCHEMBL15247491 | 0.77 | PDE10A (0.38) | PDE10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828540-B2 | Compositions for treating subterranean formations | HALLIBURTON ENERGY SERVICES, INC. (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160230066-A1 | COMPOSITIONS FOR TREATING SUBTERRANEAN FORMATIONS | HALLIBURTON ENERGY SERVICES, INC. | 2016-08-11 | — | — | US | disclosed |
| US-20150344437-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | THE JOHNS HOPKINS UNIVERSITY | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344437-A1 | PYRAZOLONE DERIVATIVES AS NITROXYL DONORS | TNNI3, PFKP, NOX5 | MEN1 3991/4885KMT2A 4665/4885MAPK1 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.