Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR2 | P41597 | 3/20 | 0.46 |
| ▸ | CPS1 | P31327 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833732 | 0.93 | DGAT1 (0.58) | DGAT1CCR1CCR2CPS1ALDH1A1 | |
| SCHEMBL13427 | 0.93 | DGAT1 (0.58) | DGAT1CCR1CCR2CPS1ALDH1A1 | |
| SCHEMBL30619309 | 0.86 | DGAT1 (0.50) | DGAT1CCR1CCR2CPS1ALDH1A1 | |
| SCHEMBL873620 | 0.83 | ALDH1A1 (0.42) | DGAT1CCR1CCR2ALDH1A1LMNA | |
| SCHEMBL20473911 | 0.81 | DGAT1 (0.49) | DGAT1CCR1CCR2ALDH1A1LMNA | |
| SCHEMBL21414817 | 0.81 | DGAT1 (0.49) | DGAT1CCR1CCR2ALDH1A1LMNA | |
| SCHEMBL25804407 | 0.81 | DGAT1 (0.49) | DGAT1CCR1CCR2ALDH1A1LMNA | |
| SCHEMBL20473896 | 0.81 | DGAT1 (0.49) | DGAT1CCR1CCR2ALDH1A1LMNA | |
| SCHEMBL26187493 | 0.81 | DGAT1 (0.49) | DGAT1CPS1ALDH1A1LMNANPC1 | |
| SCHEMBL1260625 | 0.81 | CES2 (0.43) | CCR1CCR2LMNANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540565-B2 | Liquid crystal compounds containing dibenzopyran derivatives of naphthenic base and application thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2017-01-10 | — | — | US | disclosed |
| US-20160230092-A1 | LIQUID CRYSTAL COMPOUNDS CONTAINING DIBENZOPYRAN DERIVATIVES OF NAPHTHENIC BASE AND APPLICATION THEREOF | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD (CN) | 2016-08-11 | — | — | US | disclosed |