Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997452 | 0.91 | PTGS2 (0.57) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL17997442 | 0.90 | PTGS2 (0.56) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL17997445 | 0.87 | PTGS2 (0.45) | PTGS2MEN1KMT2AATMAKR1C3 | |
| SCHEMBL2528716 | 0.85 | PTGS2 (0.59) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL2528717 | 0.84 | PTGS2 (0.57) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL17997476 | 0.82 | PTGS2 (0.49) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL6820125 | 0.82 | HPGD (0.57) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL17997457 | 0.81 | PTGS2 (0.50) | PTGS2HPGDATMNPC1RAB9A | |
| SCHEMBL6293915 | 0.81 | PTGS2 (0.57) | PTGS2HPGDMEN1KMT2ANPC1 | |
| SCHEMBL6762775 | 0.81 | PTGS2 (0.57) | PTGS2HPGDMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |