Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997452 | 0.98 | PTGS2 (0.57) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL2528716 | 0.92 | PTGS2 (0.59) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL2528717 | 0.91 | PTGS2 (0.57) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL17997443 | 0.90 | PTGS2 (0.49) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL17997476 | 0.90 | PTGS2 (0.49) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL6820125 | 0.89 | HPGD (0.57) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL17997457 | 0.88 | PTGS2 (0.50) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL6293915 | 0.87 | PTGS2 (0.57) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL6762775 | 0.87 | PTGS2 (0.57) | PTGS2HPGDNPC1RAB9AESR1 | |
| SCHEMBL17997465 | 0.87 | RAPGEF4 (0.53) | PTGS2HPGDNPC1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |