Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997452 | 0.91 | PTGS2 (0.57) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL17997442 | 0.90 | PTGS2 (0.56) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL17997456 | 0.89 | PTGS2 (0.39) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2528716 | 0.85 | PTGS2 (0.59) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL17997465 | 0.85 | RAPGEF4 (0.53) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL17997449 | 0.84 | PTGS2 (0.48) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2528717 | 0.84 | PTGS2 (0.57) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL7044776 | 0.84 | PTGS2 (0.47) | PTGS2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL17997457 | 0.84 | PTGS2 (0.50) | PTGS2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL17997464 | 0.83 | PTGS2 (0.44) | PTGS2NPC1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160231658-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2016-08-11 | — | — | US | disclosed |