Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003968 | 0.85 | ADORA1 (0.45) | ERBB2ALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL18004136 | 0.85 | ADORA1 (0.45) | ERBB2ALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL12386160 | 0.85 | ERBB2 (0.46) | ERBB2ALDH1A1CYP1A2CYP2C9LMNA | |
| SCHEMBL18005932 | 0.82 | MAPT (0.40) | MAPTALDH1A1KDM4ECYP3A4TDP1 | |
| SCHEMBL18004145 | 0.81 | ERBB2 (0.40) | ERBB2ALDH1A1KDM4ELMNAADORA1 | |
| SCHEMBL18006124 | 0.80 | CNR2 (0.38) | ERBB2L3MBTL1TSHRSMN1; SMN2ADORA1 | |
| SCHEMBL4099340 | 0.79 | KMT2A (0.37) | ERBB2MAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL17969160 | 0.79 | ERBB2 (0.55) | PTGDR2ERBB2ALDH1A1SMN1; SMN2ADORA1 | |
| SCHEMBL4099342 | 0.79 | KMT2A (0.37) | ERBB2MAPTALDH1A1KDM4ECYP1A2 | |
| SCHEMBL18005953 | 0.78 | ERBB2 (0.54) | PTGDR2ERBB2ALDH1A1SMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-04-21 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10626095-B2 | Cyanotriazole compounds | CS, PC, ACAT1 | PTGDR2 4574/4885ERBB2 4040/4885MAPT 2196/4885 |
| US-20160229816-A1 | CYANOTRIAZOLE COMPOUNDS | CS, PC, ACAT1 | PTGDR2 4574/4885ERBB2 4040/4885MAPT 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.