Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 5/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | FHIT | P49789 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419736 | 0.86 | ALDH1A1 (0.69) | MAPTALDH1A1HPGDTDP1GRM6 | |
| SCHEMBL1796571 | 0.85 | GRM6 (0.53) | MAPTALDH1A1HPGDTDP1GRM6 | |
| SCHEMBL10489614 | 0.84 | TP53 (0.55) | MAPTALDH1A1HPGDTDP1GRM6 | |
| SCHEMBL1800474 | 0.80 | ALDH1A1 (0.52) | MAPTALDH1A1HPGDTDP1GRM6 | |
| SCHEMBL10633454 | 0.74 | GRM6 (0.60) | MAPTALDH1A1HPGDGRM6HSD17B10 | |
| SCHEMBL1797940 | 0.73 | ALDH1A1 (0.45) | MAPTALDH1A1HPGDTP53POLB | |
| SCHEMBL14699510 | 0.71 | GRM6 (0.55) | MAPTALDH1A1HPGDGRM6HSD17B10 | |
| SCHEMBL2180324 | 0.71 | ALDH1A1 (0.74) | MAPTALDH1A1HPGDTDP1GRM6 | |
| SCHEMBL7690980 | 0.70 | CSNK1A1 (0.68) | ALDH1A1HPGDGRM6HSD17B10CDC7 | |
| SCHEMBL4000814 | 0.69 | MAPT (0.56) | MAPTALDH1A1HPGDTDP1GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951806-B2 | Plasminogen activator inhibitor-1 inhibitor | RENASCIENCE CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | RENASCIENCE CO., LTD. (JP) | 2009-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124620-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | SERPINE1, SERPINC1, SERPINB1 | MAPT 2975/4885ALDH1A1 800/4885HPGD 920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.