Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18007446 | 0.88 | HRH3 (0.38) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL18009330 | 0.88 | HRH3 (0.38) | SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL18009211 | 0.82 | GLA (0.34) | PKMSMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL18009194 | 0.81 | PEPD (0.39) | PIK3CDALDH1A1 | |
| SCHEMBL18009192 | 0.81 | PIK3CD (0.36) | ATMPIK3CD | |
| SCHEMBL18007444 | 0.81 | TSHR (0.41) | SMN1; SMN2TSHRATMALDH1A1POLB | |
| SCHEMBL18007441 | 0.80 | PIN1 (0.35) | PIK3CD | |
| SCHEMBL18009386 | 0.79 | ALDH1A1 (0.35) | SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL18009372 | 0.78 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL18009295 | 0.78 | PIK3CD (0.34) | PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |