Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18009292 | 0.84 | PIK3CD (0.41) | TSHRMAPTKMT2AALDH1A1HTT | |
| SCHEMBL18009294 | 0.83 | MMP2 (0.46) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18009330 | 0.83 | HRH3 (0.38) | ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL18007446 | 0.83 | HRH3 (0.38) | ALDH1A1POLBHPGDSMN1; SMN2 | |
| SCHEMBL18009461 | 0.82 | PIK3CD (0.40) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18009293 | 0.81 | KDM4E (0.42) | TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18007451 | 0.81 | PIK3CD (0.39) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18009338 | 0.81 | PKM (0.34) | TSHRATMALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL18007449 | 0.79 | PIK3CD (0.36) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL18009283 | 0.79 | ALDH1A1 (0.40) | TSHRMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016127186-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2016-08-11 | — | — | WO | disclosed |