SCHEMBL1801033

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1801036	0.93	HPGDS (0.59)	HPGDSPRSS12ALDH1A1SMN1; SMN2LMNA
	SCHEMBL1801708	0.86	HPGDS (0.44)	HPGDSPRSS12ALDH1A1SMN1; SMN2LMNA
	SCHEMBL1803024	0.86	HPGDS (0.56)	HPGDSALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL1799466	0.85	HPGDS (0.55)	HPGDSALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL1801860	0.83	HPGDS (0.49)	HPGDSALDH1A1HPGDKDM4EMEN1
	SCHEMBL1801799	0.83	HPGDS (0.54)	HPGDSALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL1803213	0.83	HPGDS (0.54)	HPGDSALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL1802043	0.83	HPGDS (0.59)	HPGDSALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL1803457	0.82	HPGDS (0.57)	HPGDSALDH1A1SMN1; SMN2LMNAHPGD
	SCHEMBL1802167	0.82	HPGDS (0.49)	HPGDSALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.