Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.58 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.54 |
| ▸ | TDP2 | O95551 | 14/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22526396 | 0.78 | PARP1 (0.54) | CDK5PARP10PARP11TDP2CASP3 | |
| SCHEMBL22904170 | 0.78 | TDP2 (0.52) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL22904534 | 0.78 | PARP1 (0.54) | CDK5TDP2CASP3CASP7CASP9 | |
| SCHEMBL29444532 | 0.77 | CDK5 (0.54) | CDK5PIM1CSNK1A1ROCK1DYRK1A | |
| SCHEMBL19938 | 0.77 | CDK5 (0.54) | CDK5PIM1CSNK1A1ROCK1DYRK1A | |
| SCHEMBL24029524 | 0.75 | TDP2 (0.49) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL24778047 | 0.75 | TDP2 (0.47) | CDK5PIM1CSNK1A1ROCK1DYRK1A | |
| SCHEMBL25123374 | 0.75 | GSK3B (0.50) | CDK5TDP2CASP3CASP7CASP9 | |
| SCHEMBL38660434 | 0.74 | CDK5 (0.52) | CDK5PIM1CSNK1A1ROCK1DYRK1A | |
| SCHEMBL22525285 | 0.74 | TDP2 (0.47) | CDK5PARP10PARP11TDP2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140631-A1 | EXO VII INHIBITOR AND QUINOLONE ANTIBIOTIC COMBINATION USEFUL FOR TREATING BACTERIAL INFECTIONS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20160243149-A1 | NOVEL ANTI-VIRAL THERAPEUTIC | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243149-A1 | NOVEL ANTI-VIRAL THERAPEUTIC | RNASEH1, DNASE1L3, DNASE1 | CDK5 2813/4885PIM1 3807/4885CSNK1A1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.