SCHEMBL18010809

SCHEMBL18010809

O=C1Cc2cc(-c3ccco3)ccc2C(=O)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18010843 0.91 TDP2 (1.00) TDP2
SCHEMBL4061399 0.82 TDP2 (0.70) TDP2
SCHEMBL5873706 0.82 TDP2 (0.70) TDP2
SCHEMBL18010841 0.79 TDP2 (1.00) TDP2
SCHEMBL18010829 0.76 TDP2 (0.94) TDP2
SCHEMBL5873962 0.74 ABL1 (0.67) TDP2
SCHEMBL18010825 0.74 TDP2 (1.00) TDP2
SCHEMBL18010831 0.74 TDP2 (1.00) TDP2
SCHEMBL18010792 0.72 TDP2 (1.00) TDP2
SCHEMBL18010791 0.72 TDP2 (1.00) TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160243149-A1 NOVEL ANTI-VIRAL THERAPEUTIC THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2016-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160243149-A1 NOVEL ANTI-VIRAL THERAPEUTIC RNASEH1, DNASE1L3, DNASE1 TDP2 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.