SCHEMBL18011012

SCHEMBL18011012

CCC[C@H](N)C(=O)NC(=O)[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SETD2 Q9BYW2 2/20 0.44
▸ SMYD3 Q9H7B4 1/20 0.44
▸ EZH2 Q15910 5/20 0.43
▸ ADORA2A P29274 3/20 0.42
▸ NSD2 O96028 1/20 0.42
▸ CARM1 Q86X55 1/20 0.42
▸ SETD7 Q8WTS6 1/20 0.42
▸ PRMT1 Q99873 1/20 0.42
▸ PI4KA P42356 2/20 0.41
▸ PI4K2B Q8TCG2 2/20 0.41
▸ PI4K2A Q9BTU6 2/20 0.41
▸ PI4KB Q9UBF8 2/20 0.41
▸ RNMT O43148 1/20 0.40
▸ ADORA3 P0DMS8 2/20 0.40
▸ TRDMT1 O14717 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ DPP4 P27487 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ SLC28A1 O00337 1/20 0.40
▸ MAP3K7 O43318 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18011010 1.00 SETD2 (0.44) SETD2SMYD3EZH2ADORA2ANSD2
SCHEMBL1300400 0.90 ADORA2A (0.41) SETD2SMYD3EZH2ADORA2ANSD2
SCHEMBL157247 0.90 ADORA2A (0.41) SETD2SMYD3EZH2ADORA2ANSD2
SCHEMBL2185027 0.88 TARS1 (0.46) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL30862415 0.88 TARS1 (0.46) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL1275036 0.88 TARS1 (0.46) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL28824008 0.84 ADORA2A (0.43) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL7226462 0.84 ADORA3 (0.51) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL15798672 0.83 ADORA3 (0.45) ADORA2API4KAPI4K2BPI4K2API4KB
SCHEMBL6536153 0.81 PI4KA (0.46) ADORA2API4KAPI4K2BPI4K2API4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12503720-B2 Multiplexed profiling of RNA and DNA modifications Alida Biosciences Inc. (US) 2025-12-23 — — US disclosed
US-20240384326-A1 MULTIPLEXED PROFILING OF RNA AND DNA MODIFICATIONS Alida Biosciences Inc. (US) 2024-11-21 — — US disclosed
US-12084713-B2 Multiplexed profiling of RNA and DNA modifications Alida Biosciences Inc. (US) 2024-09-10 — — US disclosed
US-20220298542-A1 MULTIPLEXED PROFILING OF RNA AND DNA MODIFICATIONS Alida Biosciences Inc. (US) 2022-09-22 — — US disclosed
US-20160243221-A1 COMPOSITIONS AND METHODS FOR TOLERIZING CELLULAR SYSTEMS MODERNA THERAPEUTICS, INC. (US) 2016-08-25 — — US disclosed
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