SCHEMBL2185027

SCHEMBL2185027

C[C@@H](O)[C@H](N)C(=O)NC(=O)[C@@]1(n2cnc3c(N)ncnc32)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TARS1 P26639 2/20 0.46
▸ ADORA2A P29274 3/20 0.43
▸ ADORA3 P0DMS8 4/20 0.42
▸ PI4KA P42356 2/20 0.42
▸ PI4K2B Q8TCG2 2/20 0.42
▸ PI4K2A Q9BTU6 2/20 0.42
▸ PI4KB Q9UBF8 2/20 0.42
▸ DPP4 P27487 1/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ SLC28A1 O00337 1/20 0.41
▸ MAP3K7 O43318 1/20 0.41
▸ SLC28A2 O43868 1/20 0.41
▸ GAPDH P04406 1/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ ADORA2B P29275 1/20 0.41
▸ ADORA1 P30542 1/20 0.41
▸ STAT6 P42226 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.41
▸ DOT1L Q8TEK3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30862415 1.00 TARS1 (0.46) TARS1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL1275036 1.00 TARS1 (0.46) TARS1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL31675871 0.90 AHCY (0.41) ADORA2AADORA3ADORA2BADORA1DOT1L
SCHEMBL23066313 0.88 ADORA3 (0.45) TARS1ADORA2AADORA3PI4KAPI4K2B
SCHEMBL18011012 0.88 SETD2 (0.44) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL18011010 0.88 SETD2 (0.44) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL157247 0.85 ADORA2A (0.41) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL1300400 0.85 ADORA2A (0.41) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL15798672 0.84 ADORA3 (0.45) ADORA2AADORA3PI4KAPI4K2BPI4K2A
SCHEMBL2480939 0.84 PI4KA (0.46) ADORA2AADORA3PI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191244-A1 METHOD FOR DETECTING CORONAVIRUS INFECTION 国立大学法人熊本大学 2022-09-15 — — WO claimed
EP-3387150-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY Novartis AG (CH) 2018-10-17 — — EP claimed
WO-2017098468-A1 LABEL-FREE ANALYSIS OF RNA CAPPING EFFICIENCY USING RNASE H, PROBES AND LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY NOVARTIS AG (CH) 2017-06-15 — — WO claimed
WO-2017011773-A2 CODON-OPTIMIZED NUCLEIC ACIDS ENCODING ANTIBODIES MODERNATX, INC. (US) 2017-01-19 — — WO claimed
WO-2026103936-A1 CHEMICALLY MODIFIED CIRCULAR RNA MOLECULE, PREPARATION METHOD THEREFOR, AND USE THEREOF 上海元码智药生物技术有限公司 2026-05-21 — — WO disclosed
US-20260138117-A1 ADSORPTION TECHNOLOGY THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2026-05-21 — — US disclosed
WO-2026107144-A1 RNA SEQUENCE FOR EXPRESSING PROTEIN IN CARDIOMYOCYTES ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2026-05-21 — — WO disclosed
CN-122060818-A Chemically modified circular RNA molecules, methods of making and uses thereof 上海元码智药生物技术有限公司 2026-05-19 — — CN disclosed
US-20260115324-A1 Chimeric Antigen Receptors Targeting CD19 ORNA THERAPEUTICS, INC. (US) 2026-04-30 — — US disclosed
EP-4731233-A1 EXTRACELLULAR VESICLES FROM REGULATORY B CELLS Institut National de la Santé et de la Recherche Médicale (FR) 2026-04-29 — — EP disclosed
US-12612658-B2 RNA replication using transcription polymerases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-04-28 — — US disclosed
US-12612624-B2 Light-inducible CRISPR/Cas9 system for genome editing THE JOHNS HOPKINS UNIVERSITY (US) 2026-04-28 — — US disclosed
WO-2010036795-A2 SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS TRANA DISCOVERY, INC. (US) 2010-04-01 — — WO disclosed
WO-2008064304-A9 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS TRANA DISCOVERY INC (US) 2008-07-10 — — WO disclosed
WO-2008064304-A2 COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS TRANA DISCOVERY, INC. (US) 2008-05-29 — — WO disclosed
EP-1263986-A4 PLATFORM FOR THE DISCOVERY OF THE BACTERIAL GENES INVOLVED IN RNA MODIFICATION TAO BIOSCIENCES LLC (US) 2005-02-23 — — EP disclosed
EP-1263986-A1 PLATFORM FOR THE DISCOVERY OF THE BACTERIAL GENES INVOLVED IN RNA MODIFICATION Montclair Group (US) 2002-12-11 — — EP disclosed
EP-1261734-A1 GENOMIC ANALYSIS OF tRNA GENE SETS Montclair Group (US) 2002-12-04 — — EP disclosed
WO-2001062981-A1 PLATFORM FOR THE DISCOVERY OF THE BACTERIAL GENES INVOLVED IN RNA MODIFICATION MONTCLAIR GROUP (US) 2001-08-30 — — WO disclosed
WO-2001062955-A1 GENOMIC ANALYSIS OF tRNA GENE SETS MONTCLAIR GROUP (US) 2001-08-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612624-B2 Light-inducible CRISPR/Cas9 system for genome editing RNMT, AMPD2, NT5C2 TARS1 3010/4885ADORA2A 196/4885ADORA3 846/4885
US-20260138117-A1 ADSORPTION TECHNOLOGY SLC6A2, PSPH, SLC10A6 TARS1 4484/4885ADORA2A 147/4885ADORA3 67/4885
US-20260115324-A1 Chimeric Antigen Receptors Targeting CD19 BCR, IGLV6-57, BCL6 TARS1 1301/4885ADORA2A 3674/4885ADORA3 4101/4885
US-12612658-B2 RNA replication using transcription polymerases RNGTT, POLRMT, POLM TARS1 755/4885ADORA2A 712/4885ADORA3 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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