SCHEMBL1123572

SCHEMBL1123572

CCCCCCCCOC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
LMNA P02545 4/20 0.65
MAPK1 P28482 2/20 0.65
TSHR P16473 3/20 0.49
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PPARG P37231 3/20 0.43
HPGD P15428 1/20 0.43
CNR2 P34972 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5331475 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL7205837 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL14877495 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL5145142 0.99 LMNA (0.66) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL502564 0.94 LMNA (0.67) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL15797630 0.93 LMNA (0.57) ALDH1A1LMNAMAPK1TSHRTDP1
SCHEMBL6344467 0.92 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL6344463 0.92 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL13236533 0.92 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL28954250 0.91 ALDH1A1 (0.55) ALDH1A1LMNAMAPK1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111358711-B Photosensitive material/calcium alginate core-shell nanocapsule dispersoid and preparation method thereof 万华化学集团股份有限公司 2023-08-11 CN claimed
CN-110917071-B Core-shell structure flexible bead, preparation method thereof and personal care product comprising core-shell structure flexible bead 万华化学集团股份有限公司 2022-11-08 CN claimed
CN-111358711-A Photosensitive material/calcium alginate core-shell nanocapsule dispersion and preparation method thereof 万华化学集团股份有限公司 2020-07-03 CN claimed
CN-110917071-A Core-shell structure flexible bead, preparation method thereof and personal care product comprising core-shell structure flexible bead 上海万华科聚化工科技发展有限公司 2020-03-27 CN claimed
EP-0655908-B1 COSMETIC FILTERING COMPOSITIONS CONTAINING A HYDROPHILIC AGENT WITH AT LEAST ONE SULPHONIC ACID RADICAL OREAL (FR) 1999-01-07 EP claimed
US-5635163-A Screening cosmetic compositions containing a hydrophilic agent comprising at least one sulphonic acid radical L'OREAL (FR) 1997-06-03 US claimed
US-12576017-B2 Sunscreen composition with enhanced photoprotection EDGEWELL PERSONAL CARE BRANDS, LLC (US) 2026-03-17 US disclosed
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
CN-113383048-B Antireflection film with pressure-sensitive adhesive layer, self-luminous display device, and method for manufacturing same 日东电工株式会社 2024-10-22 CN disclosed
WO-2024185433-A1 ACTIVE ENERGY RAY CURABLE COMPOSITION, LAMINATE, AND METHOD FOR MANUFACTURING LAMINATE DIC株式会社 2024-09-12 WO disclosed
CN-116261491-B Coating agent for plexiglass and plexiglass 株式会社丰田自动织机 2024-07-02 CN disclosed
US-20240207152-A1 SUNSCREEN COMPOSITION WITH ENHANCED PHOTOPROTECTION EDGEWELL PERSONAL CARE BRANDS, LLC 2024-06-27 US disclosed
US-20240117195-A1 COATING AGENT FOR RESIN GLASS, AND RESIN GLASS KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2024-04-11 US disclosed
US-4353965-A SOLVENT AND WEATHER RESISTANCE, ADHESION GENERAL ELECTRIC COMPANY (US) 1982-10-12 US disclosed
US-4353959-A Abrasion resistant silicone coated polycarbonate article having an acrylic primer layer containing a U.V. absorbing compound GENERAL ELECTRIC COMPANY (US) 1982-10-12 US disclosed
US-4308317-A PRIMER LAYER OF SPECIFIED THICKNESS COMPRISING THERMOSET ACRYLIC POLYMER GENERAL ELECTRIC COMPANY (US) 1981-12-29 US disclosed
US-4284685-A Abrasion resistant silicone coated polycarbonate article GENERAL ELECTRIC COMPANY (US) 1981-08-18 US disclosed
US-4242383-A THERMOSETTING ACRYLIC PRIMER WITH BENZYLIDENE MALONATE OR CYANOACRYLATE UV ABSORBER GENERAL ELECTRIC COMPANY (US) 1980-12-30 US disclosed
US-4242381-A THERMOSETTING ACRYLIC PRIMER WITH BENZYLIDENE MALONATE OR CYANOACRYLATE UV ABSORBER GENERAL ELECTRIC COMPANY (US) 1980-12-30 US disclosed
US-3997464-A 1-HYDROXY-4-(P-TOLUIDINO)-9,10-ANTHRAQUINONE, A COPPER PHTHALOCYANINE TRISULFONAMIDE, UV ABSORBER AMERICAN CYANAMID COMPANY (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207152-A1 SUNSCREEN COMPOSITION WITH ENHANCED PHOTOPROTECTION MMS19, SUN2, ERCC1 ALDH1A1 318/4885LMNA 1305/4885MAPK1 4135/4885
US-12576017-B2 Sunscreen composition with enhanced photoprotection TELO2, AS3MT, TYR ALDH1A1 1389/4885LMNA 3703/4885MAPK1 4199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.