SCHEMBL7205837

SCHEMBL7205837

CCCCCCOC(=O)C(C#N)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
LMNA P02545 4/20 0.65
MAPK1 P28482 2/20 0.65
TSHR P16473 3/20 0.49
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PPARG P37231 3/20 0.43
HPGD P15428 1/20 0.43
CNR2 P34972 1/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
MAPT P10636 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5331475 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL14877495 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL1123572 1.00 ALDH1A1 (0.65) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL5145142 0.99 LMNA (0.66) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL502564 0.94 LMNA (0.67) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL15797630 0.93 LMNA (0.57) ALDH1A1LMNAMAPK1TSHRTDP1
SCHEMBL6344467 0.92 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL6344463 0.92 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL13236533 0.92 ALDH1A1 (0.56) ALDH1A1LMNAMAPK1TSHRTP53
SCHEMBL28954250 0.91 ALDH1A1 (0.55) ALDH1A1LMNAMAPK1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115003388-A Aqueous sunscreen formulations based on sulfated crystalline cellulose SPF boosters 陶氏环球技术有限责任公司 2022-09-02 CN disclosed
CN-108883316-A Skin-lightening, sunscreen, vitamin D-generating compositions 欧内斯特·阿姆斯特朗 2018-11-23 CN disclosed
CN-108603018-A Polycarbonate resin composition and molded article thereof 三菱化学株式会社 2018-09-28 CN disclosed
CN-108403459-A Use of diethylamino hydroxybenzoyl hexyl benzoate in cosmetic sunscreen agent 拜尔斯道夫股份有限公司 2018-08-17 CN disclosed
CN-107922720-A Polycarbonate resin composition, method for producing same, and molded article 华东理工大学 2018-04-17 CN disclosed
EP-2847784-A1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION Cabot Microelectronics Corporation (US) 2015-03-18 EP disclosed
US-20140134120-A1 PHOTOPROTECTIVE COMPOSITION L'OREAL (FR) 2014-05-15 US disclosed
WO-2013154913-A1 POLISHING PAD WITH LIGHT-STABLE LIGHT-TRANSMITTING REGION CABOT MICROELECTRONICS CORPORATION (US) 2013-10-17 WO disclosed
CN-1162144-C Ultraviolet absorbing composition ������������ʽ���� 2004-08-18 CN disclosed
EP-0828473-B1 A COSMETIC PRODUCT TO PREVENT AND CORRECT SKIN DAMAGE UNILEVER NV (NL) 2003-07-09 EP disclosed
EP-0547864-B1 Self-tanner cosmetic composition UNILEVER PLC (GB) 1998-09-09 EP disclosed
EP-0828473-A1 A COSMETIC PRODUCT TO PREVENT AND CORRECT SKIN DAMAGE UNILEVER N.V. (NL) 1998-03-18 EP disclosed
CN-1172641-A Ultraviolet absorbing composition SHISEIDO CO LTD (JP) 1998-02-11 CN disclosed
EP-0501714-B1 Cationic compositions for skin UNILEVER PLC (GB) 1997-05-02 EP disclosed
US-5612044-A MULTICOMPARTMENT DISPENSER FOR STORING A FIRST AND SECOND SUBSTANCE ELIZABETH ARDEN COMPANY, DIVISION OF CONOPCO, INC. (US) 1997-03-18 US disclosed
WO-1996037179-A1 A COSMETIC PRODUCT TO PREVENT AND CORRECT SKIN DAMAGE UNILEVER PLC (GB) 1996-11-28 WO disclosed
WO-1994020066-A1 SUNSCREEN COMPOSITION UNILEVER PLC (GB) 1994-09-15 WO disclosed
US-5306486-A Residue-free ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) 1994-04-26 US disclosed
US-5169624-A Quaternary ammonium phosphate ester, cationic polysaccharide, sunscreen agent CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-12-08 US disclosed
US-4131463-A Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system FUJI PHOTO FILM CO., LTD. (JP) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134120-A1 PHOTOPROTECTIVE COMPOSITION BROX, PLIN5, COX5A ALDH1A1 2061/4885LMNA 1334/4885MAPK1 3674/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.