SCHEMBL18014757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18014760	0.89	HSD11B1 (0.45)	TRPV3HSD17B14HSD17B1HSD17B2CNR1
	SCHEMBL2609346	0.85	TRPV3 (0.45)	TRPV3MEN1NPC1CASP3RAB9A
	SCHEMBL18014721	0.85	CNR2 (0.51)	TRPV3HSD17B14CNR1CNR2IRAK4
	SCHEMBL18014761	0.81	TRPV3 (0.40)	TRPV3CNR1CNR2IRAK4PFKFB3
	SCHEMBL18014723	0.78	CNR2 (0.47)	TRPV3CNR1CNR2HSD11B1MAP4K4
	SCHEMBL18014758	0.78	HSD11B1 (0.39)	TRPV3MEN1NPC1RAB9AKMT2A
	SCHEMBL18014762	0.78	CNR1 (0.35)	TRPV3CNR1CNR2IRAK4MAP4K4
	SCHEMBL18014763	0.77	ABL1 (0.41)	TRPV3NPC1RAB9ACNR1CNR2
	SCHEMBL18014759	0.76	CTSS (0.52)	TRPV3ATMCNR1CNR2
	SCHEMBL18014755	0.76	CTSA (0.38)	TRPV3NPC1CASP3RAB9ASENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.