Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021324 | 0.93 | LDHA (0.36) | TGFBR1LDHAMAPK14TOP1GCGR | |
| SCHEMBL19833451 | 0.93 | LDHA (0.36) | TGFBR1LDHAMAPK14TOP1GCGR | |
| SCHEMBL19794451 | 0.92 | LDHA (0.43) | TGFBR1LDHATOP1 | |
| SCHEMBL18015373 | 0.91 | PIM1 (0.35) | TGFBR1LDHAALOX5APFEN1 | |
| SCHEMBL19794361 | 0.91 | TGFBR1 (0.41) | TGFBR1MAPK14TOP1GCGRSCD | |
| SCHEMBL18015376 | 0.88 | LDHA (0.42) | TGFBR1LDHATOP1 | |
| SCHEMBL18015381 | 0.88 | LDHA (0.40) | TGFBR1LDHAMAPTALOX5APFEN1 | |
| SCHEMBL21477364 | 0.87 | IDO1 (0.35) | TGFBR1LDHAMAPK14TOP1GCGR | |
| SCHEMBL19833453 | 0.87 | LDHA (0.39) | TGFBR1LDHAALOX5APFEN1AAK1 | |
| SCHEMBL18015382 | 0.86 | TGFBR1 (0.43) | TGFBR1LDHAMAPK14TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | TGFBR1 2080/4885LDHA 2726/4885MAPK14 4612/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | TGFBR1 4348/4885LDHA 1917/4885MAPK14 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.