Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 6/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.36 |
| ▸ | CAMKK2 | Q96RR4 | 8/20 | 0.36 |
| ▸ | CAMKK1 | Q8N5S9 | 3/20 | 0.36 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | SGK3 | Q96BR1 | 1/20 | 0.36 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19794376 | 0.87 | HSD17B1 (0.40) | HSD17B1HSD17B2FEN1ALOX5APKDM1A | |
| SCHEMBL21125575 | 0.86 | HSD17B1 (0.42) | HSD17B1HSD17B2FEN1ALOX5APIRAK4 | |
| SCHEMBL16905550 | 0.85 | HSD17B1 (0.49) | HSD17B1HSD17B2FEN1ALOX5APCAMKK2 | |
| SCHEMBL23956040 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2FEN1ALOX5APCAMKK2 | |
| SCHEMBL21125448 | 0.82 | KDM1A (0.40) | HSD17B1HSD17B2FEN1KDM1ACHRNB2 | |
| SCHEMBL21662274 | 0.79 | HSD17B1 (0.36) | HSD17B1HSD17B2CAMKK2CAMKK1SGK1 | |
| SCHEMBL19801345 | 0.79 | HSD17B1 (0.34) | HSD17B1HSD17B2FEN1ALOX5APKDM1A | |
| SCHEMBL21125931 | 0.79 | HSD17B1 (0.56) | HSD17B1HSD17B2FEN1HPGDS | |
| SCHEMBL21937205 | 0.79 | CNR2 (0.34) | FEN1ALOX5AP | |
| SCHEMBL19794387 | 0.79 | HSD17B1 (0.41) | HSD17B1HSD17B2CAMKK2CAMKK1SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | HSD17B1 4860/4885HSD17B2 4834/4885FEN1 1267/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HSD17B1 4527/4885HSD17B2 4245/4885FEN1 2174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.