SCHEMBL1801574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1803359	0.87	USP2 (0.52)	RIPK1ALDH1A1SMN1; SMN2USP2TSHR
	SCHEMBL1801790	0.87	RIPK1 (0.48)	RIPK1ALDH1A1MEN1KMT2AKDM4E
	SCHEMBL1802929	0.86	KDM4E (0.45)	RIPK1ALDH1A1MEN1KMT2AKDM4E
	SCHEMBL1801500	0.86	TACR1 (0.42)	RIPK1ALDH1A1MEN1KMT2AKDM4E
	SCHEMBL1802733	0.85	RIPK1 (0.54)	RIPK1ALDH1A1MEN1KMT2AKDM4E
	SCHEMBL1797061	0.84	RIPK1 (0.50)	RIPK1MEN1KMT2ACYP2D6USP2
	SCHEMBL1803894	0.83	RIPK1 (0.51)	RIPK1ALDH1A1MEN1KMT2AMAPT
	SCHEMBL1802555	0.82	USP2 (0.52)	RIPK1ALDH1A1MEN1KMT2AMAPT
	SCHEMBL1799572	0.82	GRIA3 (0.46)	RIPK1ALDH1A1MEN1KMT2AKDM4E
	SCHEMBL1801195	0.82	RIPK1 (0.47)	RIPK1ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.