Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.82 |
| ▸ | TOP1 | P11387 | 4/20 | 0.50 |
| ▸ | CYCS | P99999 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tmpyp4 SCHEMBL265519 | 0.92 | TERT (0.97) | TERTTOP1CYCSABCG2ENPP2 | |
| Tmpyp4 SCHEMBL29369473 | 0.91 | TERT (1.00) | TERTTOP1CYCSABCG2ENPP2 | |
| Tmpyp4 SCHEMBL20380171 | 0.91 | TERT (0.93) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL29693624 | 0.89 | TERT (0.62) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL242168 | 0.89 | TERT (0.62) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL25407804 | 0.87 | TERT (0.65) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL31182124 | 0.87 | TERT (0.60) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL31268231 | 0.87 | TERT (0.60) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL31040346 | 0.87 | TERT (0.60) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL31375135 | 0.87 | TERT (0.60) | TERTTOP1CYCSABCG2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160235865-A1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN-TARGETED PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235865-A1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN-TARGETED PHOTOSENSITIZERS FOR PHOTODYNAMIC THERAPY | FOLH1, KLK3, UROD | TERT 4221/4885TOP1 2383/4885CYCS 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.