Tmpyp4

Tmpyp4

SCHEMBL265519

C[n+]1ccc(-c2c3nc(c(-c4cc[n+](C)cc4)c4ccc([nH]4)c(-c4cc[n+](C)cc4)c4nc(c(-c5cc[n+](C)cc5)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.97
▸ TOP1 P11387 4/20 0.53
▸ CYCS P99999 3/20 0.51
▸ ENPP2 Q13822 1/20 0.50
▸ ABCG2 Q9UNQ0 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tmpyp4 SCHEMBL20380171 0.98 TERT (0.93) TERTTOP1CYCSENPP2ABCG2
Tmpyp4 SCHEMBL29369473 0.98 TERT (1.00) TERTTOP1CYCSENPP2ABCG2
SCHEMBL20380004 0.94 TERT (0.85) TERTTOP1CYCSENPP2
SCHEMBL20379925 0.94 TERT (0.85) TERTTOP1CYCSENPP2
SCHEMBL20380012 0.94 TERT (0.85) TERTTOP1CYCSENPP2
SCHEMBL18016429 0.92 TERT (0.82) TERTTOP1CYCSENPP2ABCG2
SCHEMBL15580415 0.91 TERT (0.80) TERTTOP1CYCSENPP2ABCG2
SCHEMBL20705304 0.89 TERT (0.78) TERTTOP1CYCSENPP2
SCHEMBL10724093 0.84 TERT (0.68) TERTTOP1CYCSENPP2ABCG2
SCHEMBL10724268 0.83 TERT (0.67) TERTTOP1CYCSENPP2ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12433964-B2 Antiviral and antibacterial disinfection aero-solution using edible food dyes PURDUE RESEARCH FOUNDATION (US) 2025-10-07 — — US claimed
CN-119912657-A C-C single bond connected ionic covalent organic framework and preparation method and application thereof 天津市生态环境科学研究院(天津市环境规划院、天津市低碳发展研究中心) 2025-05-02 — — CN claimed
CN-119455901-A Preparation method of blood perfusion diagnosis and treatment device based on guanosine supermolecular gel 广州医科大学附属第一医院(广州呼吸中心) 2025-02-18 — — CN claimed
CN-112366278-B Composite transmission layer, application thereof and preparation method of organic solar cell module 陕西科技大学 2024-11-26 — — CN claimed
CN-118993570-A Enhancement of SnS by controlled electrodepositing porphyrins2Method for nonlinear optical performance of nano-sheet 同济大学 2024-11-22 — — CN claimed
CN-117169202-A CH for regulating AuNPs aggregation based on interaction of target and DNA dye 3 Hg + Detection method 成都理工大学 2023-12-05 — — CN claimed
US-20230313452-A1 Textile Fabric, Clothing, Method for Producing or Functionalizing a Textile Fabric and Uses of a Photosensitizer Bonded to a Textile Fabric ORTNER CLEANROOM ENGINEERING GMBH (AT) 2023-10-05 — — US claimed
CN-109152358-B Photosensitizer dispersions and uses thereof 特里奥普托泰克有限公司 2023-07-07 — — CN claimed
CN-115887643-A Preparation method and application of DNA nano immunotherapy drug for photoresponse delivery of PDL1 aptamer 郑州大学 2023-04-04 — — CN claimed
CN-115735030-A Textile fabric, clothing, method for producing or functionalizing a textile fabric, and use of a photosensitizer incorporated in a textile fabric 奥特纳洁净室工程有限公司 2023-03-03 — — CN claimed
CN-113072936-B Fluorescent probe based on carbon quantum dot-porphyrin assembly system and preparation method and application thereof 上海大学 2022-11-04 — — CN claimed
CN-110295217-B Method for applying quantum dot doped ratiometric fluorescent probe to microRNA in-vitro detection 东南大学 2022-09-20 — — CN claimed
CN-110200966-B Application of G4 ligand TMPyP4 in preparation of medicine for resisting porcine reproductive and respiratory syndrome virus 河南牧业经济学院 2022-08-12 — — CN claimed
CN-111440349-B Preparation method of sodium alginate antibacterial dressing 中国石油大学(华东) 2022-05-27 — — CN claimed
CN-111272848-B High-sensitivity photoelectrochemical biosensor for detecting miRNA159c and preparation and detection methods thereof 安徽大学 2022-04-26 — — CN claimed
US-11039616-B2 Photodynamic compositions, methods of making, and uses thereof NORTH CAROLINA STATE UNIVERSITY (US) 2021-06-22 — — US claimed
US-8133739-B2 Reagent for measurement of concentration of lead, and method for measurement of concentration of lead KOWA CO., LTD. (JP) 2012-03-13 — — US claimed
US-12616204-B2 Use of cationic porphyrins as selective herbicide UNIVERSITE DE LIMOGES (FR) 2026-05-05 — — US disclosed
US-20040063681-A1 Methods for using gold (III) complexes as anti-tumor and anti-HIV agents CHE CHI-MING (CN) 2004-04-01 — — US disclosed
WO-2004024146-A1 METHODS FOR USING GOLD (III) COMPLEXES AS ANTI-TUMOR AND ANTI-HIV AGENTS THE UNIVERSITY OF HONG KONG (CN) 2004-03-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616204-B2 Use of cationic porphyrins as selective herbicide PPOX, HMOX1, TDO2 TERT 3025/4885TOP1 186/4885CYCS 258/4885
US-20040063681-A1 Methods for using gold (III) complexes as anti-tumor and anti-HIV agents HCCS, ME3, IDH1 TERT 1918/4885TOP1 71/4885CYCS 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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