Tmpyp4

Tmpyp4

SCHEMBL29369473

C[n+]1ccc(-c2c3nc(c(-c4cc[n+](C)cc4)c4ccc([nH]4)c(-c4cc[n+](C)cc4)c4ccc([nH]4)c(-c4cc[n+](C)cc4)c4nc2C=C4)C=C3)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 1.00
▸ CYCS P99999 3/20 0.54
▸ ENPP2 Q13822 1/20 0.53
▸ TOP1 P11387 4/20 0.51
▸ ABCG2 Q9UNQ0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tmpyp4 SCHEMBL265519 0.98 TERT (0.97) TERTCYCSENPP2TOP1ABCG2
Tmpyp4 SCHEMBL20380171 0.97 TERT (0.93) TERTCYCSENPP2TOP1ABCG2
SCHEMBL20379925 0.92 TERT (0.85) TERTCYCSENPP2TOP1
SCHEMBL20380004 0.92 TERT (0.85) TERTCYCSENPP2TOP1
SCHEMBL20380012 0.92 TERT (0.85) TERTCYCSENPP2TOP1
SCHEMBL18016429 0.91 TERT (0.82) TERTCYCSENPP2TOP1ABCG2
SCHEMBL15580415 0.89 TERT (0.80) TERTCYCSENPP2TOP1ABCG2
SCHEMBL20705304 0.88 TERT (0.78) TERTCYCSENPP2TOP1
Tmpyp4 SCHEMBL6045450 0.83 TERT (0.98) TERTCYCSENPP2TOP1ABCG2
SCHEMBL10724093 0.82 TERT (0.68) TERTCYCSENPP2TOP1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 376 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605407-B2 Methods to induce terminal differentiation in stem cells by interfering with DNA replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2026-04-21 — — US claimed
WO-2025262471-A1 MULTIPLEX CANCER CELL PROFILING USING MS-TAGGED PROBES CONTAINING AN IMINOSYDNONE CLEAVABLE LINKER COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2025-12-26 — — WO claimed
EP-4667939-A1 MULTIPLEX CANCER CELL PROFILING USING MS-TAGGED PROBES CONTAINING AN IMINOSYDNONE CLEAVABLE LINKER Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2025-12-24 — — EP claimed
EP-4222500-B1 METHODS OF DETECTING ISOASPARTIC ACID AMGEN INC (US) 2025-11-12 — — EP claimed
US-20250281502-A1 NEW DRUG APPLICATION CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2025-09-11 — — US claimed
EP-3813852-B1 METHODS TO INDUCE TERMINAL DIFFERENTIATION IN STEM CELLS BY INTERFERING WITH DNA REPLICATION, METHODS OF INDUCING PANCREATIC DIFFERENTIATION, AND DIFFERENTIATED CELLS OBTAINED THEREOF UNIV COLUMBIA (US) 2025-07-30 — — EP claimed
CN-119770484-A Application of porphyrin compound in preparation of medicine for treating social dysfunction 东北师范大学 2025-04-08 — — CN claimed
CN-119564697-A Application of G four-chain ligand and entecavir combined medication in anti HBV infection 武汉大学 2025-03-07 — — CN claimed
EP-3911751-B1 LIVER-SPECIFIC INDUCIBLE PROMOTERS AND METHODS OF USE THEREOF ASKBIO INC (US) 2025-02-26 — — EP claimed
CN-119394745-A Rice flour standard substance containing organic phosphorus flame retardant and preparation method thereof 中国计量科学研究院 2025-02-07 — — CN claimed
US-20220390421-A1 MATERIALS AND METHODS FOR MASS SPECTROMETRIC PROTEIN ANALYSIS JANSSEN BIOTECH, INC. 2022-12-08 — — US claimed
US-20220372582-A1 TERT PROMOTER MUTATIONS IN CANCER THE JOHNS HOPKINS UNIVERSITY 2022-11-24 — — US claimed
EP-4042152-A1 MATERIALS AND METHODS FOR MASS SPECTROMETRIC PROTEIN ANALYSIS Janssen Biotech, Inc. (US) 2022-08-17 — — EP claimed
CN-110200966-B Application of G4 ligand TMPyP4 in preparation of medicine for resisting porcine reproductive and respiratory syndrome virus 河南牧业经济学院 2022-08-12 — — CN claimed
WO-2022165398-A1 METHODS FOR TREATING AND AMELIORATING CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 — — WO claimed
CN-114829927-A Materials and methods for mass spectrometry protein analysis 詹森生物科技公司 2022-07-29 — — CN claimed
CN-114588793-A Mixed matrix membrane for methane/nitrogen separation and preparation method thereof 中国石油大学(华东) 2022-06-07 — — CN claimed
CN-114306602-A Application of targeted TERT in regulating skin and hair pigment 中国科学院上海营养与健康研究所 2022-04-12 — — CN claimed
WO-2022063307-A1 APPLICATION OF TARGETED TERT IN REGULATING SKIN AND HAIR PIGMENTS 中国科学院上海营养与健康研究所 2022-03-31 — — WO claimed
US-20220088578-A1 BIFUNCTIONAL CATALYST FOR HYDROGENATION OF CARBON DIOXIDE, AND METHOD FOR PREPARING HYDROCARBON BY USING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2022-03-24 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605407-B2 Methods to induce terminal differentiation in stem cells by interfering with DNA replication, methods of inducing pancreatic differentiation, and differentiated cells obtained thereof CCND1, CCNB3, MKI67 TERT 30/4885CYCS 1269/4885ENPP2 3737/4885
US-20220088578-A1 BIFUNCTIONAL CATALYST FOR HYDROGENATION OF CARBON DIOXIDE, AND METHOD FOR PREPARING HYDROCARBON BY USING SAME TDO2, SCO2, HAO2 TERT 58/4885CYCS 38/4885ENPP2 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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