Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | CDK11B | P21127 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14949394 | 0.92 | RAB9A (0.41) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949504 | 0.91 | KDR (0.38) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949279 | 0.87 | PDGFRB (0.37) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL625593 | 0.85 | PDGFRB (0.51) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL16330585 | 0.82 | CDK2 (0.34) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL17658736 | 0.80 | PDGFRB (0.49) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949247 | 0.79 | RAB9A (0.37) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL14949260 | 0.79 | KIT (0.37) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12348791 | 0.79 | KDR (0.45) | PDGFRBKITPDGFRACDK11BFLT3 | |
| SCHEMBL12336276 | 0.78 | PDGFRB (0.49) | PDGFRBKITPDGFRACDK11BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160237064-A1 | THERAPEUTIC METHODS AND COMPOSITIONS INVOLVING ALLOSTERIC KINASE INHIBITION | AMITECH THERAPEUTIC SOLUTIONS, INC. | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237064-A1 | THERAPEUTIC METHODS AND COMPOSITIONS INVOLVING ALLOSTERIC KINASE INHIBITION | TIE1, PRKCH, PACSIN2 | PDGFRB 486/4885KIT 799/4885PDGFRA 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.