SCHEMBL180174

SCHEMBL180174

O=C(Oc1cccc(Cl)c1Cl)Oc1cccc(Cl)c1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
MRGPRX4 Q96LA9 1/20 0.45
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 3/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HTR1D P28221 2/20 0.41
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
RHEB Q15382 1/20 0.40
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100191 0.85 TSHR (0.50) TSHRMRGPRX4HTTNPSR1ALDH1A1
SCHEMBL6969500 0.85 TSHR (0.45) TSHRMRGPRX4HTTNPSR1ALDH1A1
SCHEMBL3918667 0.85 TSHR (0.45) TSHRMRGPRX4HTTNPSR1ALDH1A1
SCHEMBL9283420 0.83 KMT2A (0.45) TSHRMRGPRX4HTTNPSR1ALDH1A1
SCHEMBL31612517 0.83 MAPK1 (0.49) TSHRMRGPRX4HTTNPSR1ALDH1A1
SCHEMBL6691258 0.83 MAPK1 (0.49) TSHRMRGPRX4HTTNPSR1ALDH1A1
SCHEMBL29450644 0.82 PTK2B (0.51) TSHRHTTALDH1A1KMT2AMEN1
SCHEMBL56863 0.82 PTK2B (0.51) TSHRHTTALDH1A1KMT2AMEN1
SCHEMBL10604766 0.82 KMT2A (0.47) TSHRMRGPRX4HTTNPSR1KMT2A
SCHEMBL3435542 0.80 TSHR (0.55) TSHRHTTNPSR1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2153928-A None JP disclosed
EP-4632027-A1 COATING MATERIAL, COATING LAYER, AND SPRING NHK Spring Co., Ltd. (JP) 2025-10-15 EP disclosed
EP-4632023-A1 COATING MATERIAL, COATING LAYER, AND SPRING NHK Spring Co., Ltd. (JP) 2025-10-15 EP disclosed
EP-4632024-A1 COATING MATERIAL AND METHOD FOR FORMING COATING LAYER NHK Spring Co., Ltd. (JP) 2025-10-15 EP disclosed
US-20250101173-A1 BIODEGRADABLE POLYCARBONATE COPOLYMER COMPRISING UNITS DERIVED FROM ANHYDROSUGAR ALCOHOL, ANHYDROSUGAR ALCOHOL-ALKYLENE GLYCOL, AND AROMATIC DIOL, METHOD FOR PRODUCING SAME, AND MOLDED PRODUCT COMPRISING SAME SAMYANG CORPORATION (KR) 2025-03-27 US disclosed
EP-4455187-A1 BIODEGRADABLE POLYCARBONATE COPOLYMER COMPRISING UNITS DERIVED FROM ANHYDROSUGAR ALCOHOL, ANHYDROSUGAR ALCOHOL-ALKYLENE GLYCOL, AND AROMATIC DIOL, METHOD FOR PRODUCING SAME, AND MOLDED PRODUCT COMPRISING SAME Samyang Corporation (KR) 2024-10-30 EP disclosed
US-20240271000-A1 COATING AGENT AND SPRING NHK SPRING CO., LTD. (JP) 2024-08-15 US disclosed
WO-2024122654-A1 COATING MATERIAL AND METHOD FOR FORMING COATING LAYER 日本発條株式会社 2024-06-13 WO disclosed
WO-2024122655-A1 COATING MATERIAL, COATING LAYER, AND SPRING 日本発條株式会社 2024-06-13 WO disclosed
WO-2024122653-A1 COATING MATERIAL, COATING LAYER, AND SPRING 日本発條株式会社 2024-06-13 WO disclosed
EP-0207688-A2 Resin composition for coating optical glass fibers NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1987-01-07 EP disclosed
US-4533728-A Process for the production of high molecular weight polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 1985-08-06 US disclosed
US-4297455-A Process for the preparation of carbonic acid aryl esters of polyester-diols lengthened via carbonate groups and their use for the preparation of polyester-diol bis-diphenol carbonates and polyester/polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed
US-4281101-A Process for the preparation of aliphatic-aromatic polycarbonates with diphenol carbonate end groups and their use for the preparation of high-molecular, segmented, aliphatic-aromatic polycarbonate elastomers which can be processed as thermoplastics BAYER AKTIENGESELLSCHAFT (DE) 1981-07-28 US disclosed
US-4267303-A Process for the preparation of polymers with diphenol carbonate end groups BAYER AKTIENGESELLSCHAFT (DE) 1981-05-12 US disclosed
US-4217437-A Process for the preparation of carbonic acid bis-diphenol esters of polyalkylene oxide-diols lengthened via carbonate groups and their use for the preparation of high-molecular, segmented polyether/polycarbonates which can be processed as thermoplastics BAYER AKTIENGESELLSCHAFT (DE) 1980-08-12 US disclosed
US-4217297-A Process for the preparation of carbonic acid aryl esters of polyester-diols lengthened via carbonate groups BAYER AKTIENGESELLSCHAFT (DE) 1980-08-12 US disclosed
US-4216298-A Process for the preparation of carbonic acid bis-diphenol esters of polyester-diols and their use for the preparation of high-molecular segmented polyester/polycarbonates which can be processed as thermoplastics BAYER AKTIENGESELLSCHAFT (DE) 1980-08-05 US disclosed
US-4191705-A Process for the preparation of carbonic acid esters of polyester-polyols BAYER AKTIENGESELLSCHAFT (DE) 1980-03-04 US disclosed
US-4031165-A BLOCK COPOLYMER TEIJIN LIMITED (JA) 1977-06-21 US disclosed