Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.76 |
| ▸ | BACE1 | P56817 | 12/20 | 0.76 |
| ▸ | BCHE | P06276 | 10/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.69 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | HTR5A | P47898 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14367985 | 0.87 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7695958 | 0.86 | HTR5A (0.77) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL1803081 | 0.86 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL28097152 | 0.85 | ACHE (0.62) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL64031 | 0.83 | CARM1 (0.63) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7696157 | 0.83 | ACHE (0.70) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL16854472 | 0.82 | CARM1 (0.57) | ACHEBACE1BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21879607 | 0.82 | CARM1 (0.62) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL18658127 | 0.82 | ACHE (0.77) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4036986 | 0.81 | ACHE (0.76) | ACHEBACE1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060271-A1 | SCREENING FOR INHIBITORS OF P. FALCIPARUM USING LUCIFERASE BASED HIGH THROUGHPUT SCREENING ASSAY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060271-A1 | SCREENING FOR INHIBITORS OF P. FALCIPARUM USING LUCIFERASE BASED HIGH THROUGHPUT SCREENING ASSAY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-19 | — | — | WO | disclosed |