Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.62 |
| ▸ | BACE1 | P56817 | 9/20 | 0.62 |
| ▸ | BCHE | P06276 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498286 | 0.90 | ACHE (0.73) | ACHEBACE1BCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2766858 | 0.89 | ACHE (0.71) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL1801792 | 0.85 | ACHE (0.76) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL7504191 | 0.81 | BCHE (0.75) | ACHEBACE1BCHE | |
| SCHEMBL1908453 | 0.81 | BCHE (0.75) | ACHEBACE1BCHE | |
| SCHEMBL1781710 | 0.81 | BCHE (0.75) | ACHEBACE1BCHE | |
| SCHEMBL13202576 | 0.79 | SIGMAR1 (0.62) | SIGMAR1KDM4EALDH1A1GLAGAA | |
| SCHEMBL8408493 | 0.79 | ACHE (0.69) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL4902967 | 0.78 | ACHE (0.64) | ACHEBACE1BCHEMEN1KMT2A | |
| SCHEMBL14367985 | 0.76 | ACHE (1.00) | ACHEBACE1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104758286-B | Application of 1-benzyl-4- (2, 4-dichlorophenethylamine) piperidine in preparation of antitumor drugs | 南京工业大学 | 2016-09-14 | — | — | CN | disclosed |