Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 10/20 | 0.51 |
| ▸ | TARS1 | P26639 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792917 | 0.84 | LARS1 (0.72) | LARS1TARS1 | |
| SCHEMBL18019204 | 0.79 | LARS1 (0.64) | LARS1 | |
| SCHEMBL19792946 | 0.77 | LARS1 (0.51) | LARS1TARS1 | |
| SCHEMBL27890559 | 0.73 | LIMK1 (0.50) | — | |
| SCHEMBL23676417 | 0.73 | FBP1 (0.56) | — | |
| SCHEMBL21667705 | 0.73 | KAT6A (0.45) | LARS1ALDH1A1 | |
| SCHEMBL23030205 | 0.72 | LARS1 (0.56) | LARS1ALDH1A1 | |
| SCHEMBL21667709 | 0.70 | NPSR1 (0.56) | ALDH1A1 | |
| SCHEMBL4974791 | 0.68 | DHFR (0.47) | LARS1TARS1 | |
| SCHEMBL19792911 | 0.67 | LARS1 (1.00) | LARS1TARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016129983-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-08-18 | — | — | WO | disclosed |