Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23676417 | 0.84 | FBP1 (0.56) | HTR6 | |
| SCHEMBL21667709 | 0.83 | NPSR1 (0.56) | HTR6ALDH1A1MMP1MMP2MMP7 | |
| SCHEMBL21667749 | 0.83 | EGFR (0.59) | EGFRERBB2ALDH1A1MMP1MMP2 | |
| SCHEMBL23030205 | 0.83 | LARS1 (0.56) | EGFRERBB2LARS1ALDH1A1MMP2 | |
| SCHEMBL18019204 | 0.83 | LARS1 (0.64) | EGFRERBB2LARS1MMP1MMP2 | |
| SCHEMBL26723622 | 0.82 | FBP1 (0.49) | KAT6AHTR6EGFRERBB2HDAC3 | |
| SCHEMBL21667756 | 0.82 | FBP1 (0.55) | — | |
| SCHEMBL6848795 | 0.79 | CA1 (0.53) | KAT6AHTR6EGFRERBB2HDAC3 | |
| SCHEMBL13649414 | 0.76 | PKM (0.54) | KAT6AHTR6HDAC3HDAC4HDAC1 | |
| SCHEMBL19801178 | 0.76 | CA1 (0.39) | EGFRERBB2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3830103-B1 | FLUORINATED BILE ACID DERIVATIVES | NZP UK LTD (GB) | 2023-11-08 | — | — | EP | disclosed |
| US-11517577-B2 | Fluorinated bile acid derivatives | NZP UK Limited (GB) | 2022-12-06 | — | — | US | disclosed |
| US-20210299148-A1 | FLUORINATED BILE ACID DERIVATIVES | NZP UK Limited (GB) | 2021-09-30 | — | — | US | disclosed |
| WO-2020025942-A1 | FLUORINATED BILE ACID DERIVATIVES | NZP UK Limited (GB) | 2020-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299148-A1 | FLUORINATED BILE ACID DERIVATIVES | NR1H4, FXR1, GPBAR1 | KAT6A 1615/4885HTR6 4220/4885EGFR 245/4885 |
| US-11517577-B2 | Fluorinated bile acid derivatives | NR1H4, FXR1, GPBAR1 | KAT6A 1615/4885HTR6 4220/4885EGFR 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.