Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 6/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650940 | 0.88 | AAK1 (0.57) | BCL2CTSSCTSKCTSBMMP13 | |
| SCHEMBL19792922 | 0.88 | AAK1 (0.57) | BCL2CTSSCTSKCTSBMMP13 | |
| SCHEMBL12213922 | 0.87 | BCL2 (0.61) | BCL2CTSSCTSKCTSBMCL1 | |
| SCHEMBL18019219 | 0.85 | AAK1 (0.59) | BCL2CTSSCTSKCTSBMCL1 | |
| SCHEMBL18019210 | 0.82 | CA2 (0.57) | BCL2CTSSCTSKCTSBAAK1 | |
| SCHEMBL1511755 | 0.81 | FLT1 (0.49) | CTSSCTSKCTSBCA1EGFR | |
| SCHEMBL31629397 | 0.81 | FLT1 (0.49) | CTSSCTSKCTSBCA1EGFR | |
| SCHEMBL19792935 | 0.78 | BCL2 (0.49) | BCL2CTSSCTSKCTSBAAK1 | |
| SCHEMBL18019121 | 0.78 | CTSK (0.48) | BCL2CTSSCTSKCTSBMMP13 | |
| SCHEMBL20548447 | 0.77 | BCL2 (0.60) | BCL2CTSSCTSKCTSBMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016129983-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2016-08-18 | — | — | WO | disclosed |