Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13474651 | 0.91 | FFAR4 (0.42) | CES2CES1TSHRFFAR4ACE2 | |
| SCHEMBL4475871 | 0.74 | CA1 (0.44) | CA1FDPSTSHRFFAR4ACE2 | |
| SCHEMBL7520001 | 0.73 | LMNA (0.41) | CES2CES1TSHRFFAR4FFAR1 | |
| SCHEMBL27889905 | 0.71 | ALDH1A1 (0.37) | CA1CES2CES1FDPSTSHR | |
| SCHEMBL22115919 | 0.71 | CES2 (0.46) | CA1CES2CES1ALDH1A1TP53 | |
| SCHEMBL434439 | 0.71 | CES2 (0.46) | CA1CES2CES1ALDH1A1TP53 | |
| SCHEMBL15941595 | 0.71 | CA1 (0.35) | CA1CES2CES1FDPSTSHR | |
| SCHEMBL22115920 | 0.71 | CES2 (0.46) | CA1CES2CES1ALDH1A1TP53 | |
| SCHEMBL11573934 | 0.71 | CA1 (0.35) | CA1CES2CES1FDPSTSHR | |
| SCHEMBL1577219 | 0.71 | CA1 (0.32) | CA1CES2CES1FDPSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225226-B1 | COMPOUNDS AND THEIR USE IN A METHOD FOR TREATMENT OF CANCER | CRITICAL OUTCOME TECHNOLOGIES INC (CA) | 2016-08-17 | — | — | EP | disclosed |