Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP10 | Q14694 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863713 | 0.84 | GSK3B (0.40) | LMNAMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL10252646 | 0.76 | USP47 (0.54) | MAPTALDH1A1GAAKMT2AUSP10 | |
| SCHEMBL1242736 | 0.76 | DAO (0.55) | LMNAMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL17977297 | 0.76 | USP10 (0.58) | LMNAMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL15577326 | 0.74 | ALDH1A1 (0.40) | LMNAMAPTALDH1A1GAAKMT2A | |
| SCHEMBL13945555 | 0.74 | PSMB8 (0.38) | LMNAMAPTALDH1A1TDP1L3MBTL1 | |
| SCHEMBL11444533 | 0.73 | TSHR (0.60) | LMNAMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL20716078 | 0.73 | LMNA (0.49) | LMNAMAPTALDH1A1L3MBTL1POLB | |
| SCHEMBL16863716 | 0.72 | ALDH1A1 (0.40) | LMNAMAPTALDH1A1GAAKMT2A | |
| SCHEMBL426359 | 0.72 | USP10 (0.51) | LMNAMAPTALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016128905-A1 | THIENOPYRROLE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-08-18 | — | — | WO | disclosed |