Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | USP10 | Q14694 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252646 | 0.85 | USP47 (0.54) | DAOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL426359 | 0.84 | USP10 (0.51) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15577326 | 0.84 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16863713 | 0.81 | GSK3B (0.40) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16863716 | 0.81 | ALDH1A1 (0.40) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL18430393 | 0.80 | HDAC6 (0.39) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3230116 | 0.79 | CA1 (0.43) | DAOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL17977297 | 0.78 | USP10 (0.58) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL11458447 | 0.78 | CA1 (0.42) | DAOKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1456043 | 0.78 | DAO (0.55) | DAOTSHRUSP47CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103467481-B | Dihydropyridine compounds, a combination thereof thing, preparation method and purposes | 上海汇伦生命科技有限公司 | 2016-08-31 | — | — | CN | disclosed |
| WO-2016128905-A1 | THIENOPYRROLE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2016-08-18 | — | — | WO | disclosed |
| WO-2014041518-A1 | THIENOPYRROLE DERIVATIVES AS ITK INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-03-20 | — | — | WO | disclosed |
| WO-2014041518-A1 | THIENOPYRROLE DERIVATIVES AS ITK INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-03-20 | — | — | WO | disclosed |
| CN-103467481-A | Dihydropyridine compounds, compositions thereof, preparation method and applications | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO LTD | 2013-12-25 | — | — | CN | disclosed |
| CN-101479253-B | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG | 2013-03-13 | — | — | CN | disclosed |
| US-8252936-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2016067-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2012-08-08 | — | — | EP | disclosed |
| US-7928231-B2 | Thienopyrazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2011-04-19 | — | — | US | disclosed |
| US-7884124-B2 | such as 2-Fluoro-4H-furo[3,2-b]pyrrole-5-carboxylate acid, used for the treatment of neuropathic pain, Alzheimer's disease, schizophrenia, ataxia and convulsions | SEPRACOR INC. (US) | 2011-02-08 | — | — | US | disclosed |
| WO-2007076228-A2 | 2-(IH-THIENO [3,2-C] PYRAZOL-3YL)-IH-INDOLE DERIVATIVES AND RELATED COMPOUNDS AS TEC KINASE INHIBITORS FOR THE TREATMENT OF INFLAMMATIONS AND IMMUNOLOGICAL DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-05 | — | — | WO | disclosed |
| EP-1682553-A1 | THIENOPYRAZOLES | Aventis Pharmaceuticals Inc. (US) | 2006-07-26 | — | — | EP | disclosed |
| EP-1664059-A1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005023819-A9 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ANGELETTI P IST RICHERCHE BIO (IT) | 2006-03-23 | — | — | WO | disclosed |
| EP-1291345-B1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | WARNER LAMBERT CO (US) | 2005-11-30 | — | — | EP | disclosed |
| US-6924276-B2 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2005-08-02 | — | — | US | disclosed |
| WO-2005026175-A1 | THIENOPYRAZOLES | AVENTIS PHARMACEUTICALS INC. (US) | 2005-03-24 | — | — | WO | disclosed |
| WO-2005023819-A1 | THIENOPYRROLES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-03-17 | — | — | WO | disclosed |
| US-20030087924-A1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | SORENSON RODERICK JOSEPH (US) | 2003-05-08 | — | — | US | disclosed |
| EP-1291345-A1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | WARNER-LAMBERT COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087924-A1 | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors | MMP13, MMP3, MMP9 | DAO 247/4885KDM4E 1800/4885MEN1 1987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.