Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623920 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL5044101 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL4236358 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL19951487 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL19034219 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL500318 | 0.71 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL4601413 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL30075378 | 0.71 | MTNR1A (0.43) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL27913426 | 0.70 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL21969422 | 0.70 | KMT2A (0.50) | ALDH1A1HPGDKDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080138908-A1 | Mass Spectrometry | THE NOGUCHI INSTITUTE (JP) | 2008-06-12 | — | — | US | claimed |
| EP-1335984-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENSOR COMPRISING A MODIFIED COENZYME A- AND ACYL-COA BINDING PROTEIN (ACBP) | Biosensor APS (DK) | 2003-08-20 | — | — | EP | claimed |
| US-20020142347-A1 | Biosensor | BIOSENSOR APS (DK) | 2002-10-03 | — | — | US | claimed |
| WO-2002061096-A1 | DETERMINATION OF HYDROPHOBIC COENZYME A ESTERS AND OTHER LIPIDS USING A BIOSENS OR COMPRISING A MODIFIED COENZYME A- AND ACYL- BINDING PROTEIN (ACBP) | BIOSENSOR APS (DK) | 2002-08-08 | — | — | WO | claimed |
| EP-2752659-B1 | MALDI MASS ANALYSIS METHOD | THE NOGUCHI INST (JP) | 2017-10-18 | — | — | EP | disclosed |
| US-20150276740-A1 | METHOD FOR DETERMINING KINASE ACTIVITY | SYSMEX CORPORATION (JP) | 2015-10-01 | — | — | US | disclosed |
| EP-1646395-B1 | METHODS AND COMPOSITIONS FOR REGULATING LYMPHOCYTE ACTIVITY | CURIS INC (US) | 2014-11-05 | — | — | EP | disclosed |
| US-20140206094-A1 | MALDI MASS SPECTROMETRY METHOD | THE NOGUCHI INSTITUTE (JP) | 2014-07-24 | — | — | US | disclosed |
| EP-2752659-A1 | MALDI MASS ANALYSIS METHOD | The Noguchi Institute (JP) | 2014-07-09 | — | — | EP | disclosed |
| US-20120269863-A1 | METHODS AND COMPOSITIONS FOR REGULATING LYMPHOCYTE ACTIVITY | CURIS, INC. (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120238500-A1 | REGULATION OF EPITHELIAL TISSUE BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO | CURIS, INC. (US) | 2012-09-20 | — | — | US | disclosed |
| US-8168178-B2 | Methods and compositions for regulating lymphocyte activity | CURIS, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| EP-0368946-A1 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0368946-A4 | 1,2-DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-05-14 | — | — | EP | disclosed |
| WO-1990000168-A1 | IMPROVED METHODS OF USING CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| WO-1990000164-A1 | NOVEL CHEMILUMINESCENT FUSED POLYCYCLIC RING-CONTAINING 1,2-DIOXETANES AND ASSAYS IN WHICH THEY ARE USED | TROPIX, INC. (US) | 1990-01-11 | — | — | WO | disclosed |
| EP-0275260-A4 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES. | QUEST SYSTEMS INC (US) | 1990-01-08 | — | — | EP | disclosed |
| WO-1989006226-A1 | SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR | QUEST SYSTEMS, INC. (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0275260-A1 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES. | QUEST SYSTEMS INC (US) | 1988-07-27 | — | — | EP | disclosed |
| WO-1988000695-A1 | METHOD OF DETECTING A SUBSTANCE USING ENZYMATICALLY-INDUCED DECOMPOSITION OF DIOXETANES | QUEST SYSTEMS, INC. (US) | 1988-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238500-A1 | REGULATION OF EPITHELIAL TISSUE BY HEDGEHOG-LIKE POLYPEPTIDES, AND FORMULATIONS AND USES RELATED THERETO | SHH, SMO, GLI1 | ALDH1A1 3638/4885HPGD 3205/4885KDM4E 4038/4885 |
| US-20120269863-A1 | METHODS AND COMPOSITIONS FOR REGULATING LYMPHOCYTE ACTIVITY | SHH, ICOS, SMO | ALDH1A1 4111/4885HPGD 1216/4885KDM4E 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.