Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18919887 | 0.89 | L3MBTL1 (0.57) | MAT2AL3MBTL1KDM4EATMMEN1 | |
| SCHEMBL9836581 | 0.88 | MAT2A (0.61) | MAT2AL3MBTL1KDM4EATMMEN1 | |
| SCHEMBL16605620 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL3334280 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL21671314 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL25010820 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL30288 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL24531917 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL16573903 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A | |
| SCHEMBL30777262 | 0.83 | L3MBTL1 (0.75) | L3MBTL1KDM4EATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257093-B1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-10249831-B2 | Electronic device containing cyclic lactams | MERCK PATENT GMBH (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| WO-2016128103-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10249831-B2 | Electronic device containing cyclic lactams | OXA1L, UROD, MRPL21 | MAT2A 4059/4885L3MBTL1 3138/4885KDM4E 2116/4885 |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | OXA1L, UROD, MRPL21 | MAT2A 4059/4885L3MBTL1 3138/4885KDM4E 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.