Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.44 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18020186 | 0.88 | MAT2A (0.54) | MAT2AL3MBTL1KDM4EATMKMT2A | |
| SCHEMBL6037518 | 0.86 | MAT2A (0.49) | MAT2AL3MBTL1KDM4EATMKMT2A | |
| SCHEMBL6037521 | 0.86 | ALDH1A1 (0.50) | MAT2AKDM4EKMT2ALMNAGAA | |
| SCHEMBL12822423 | 0.83 | MAT2A (0.75) | MAT2AL3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL15206647 | 0.82 | PDE7A (0.57) | MAT2AL3MBTL1KDM4EATMKMT2A | |
| SCHEMBL699273 | 0.81 | LMNA (0.65) | MAT2AL3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL29367625 | 0.81 | LMNA (0.65) | MAT2AL3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL22103051 | 0.80 | MAT2A (0.72) | MAT2AL3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL22093351 | 0.80 | MAT2A (0.64) | MAT2AL3MBTL1KDM4EKMT2AMEN1 | |
| SCHEMBL22093506 | 0.80 | MAT2A (0.68) | MAT2AL3MBTL1ATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725972-A1 | POLYISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024253203-A1 | POLYISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE COMPOUND | 旭化成株式会社 | 2024-12-12 | — | — | WO | disclosed |
| EP-3257093-B1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2021-07-07 | — | — | EP | disclosed |
| US-10249831-B2 | Electronic device containing cyclic lactams | MERCK PATENT GMBH (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
| WO-2016128103-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | MERCK PATENT GMBH (DE) | 2016-08-18 | — | — | WO | disclosed |
| CN-1014992-B | QUINAZOLIDIONE AND PYRIDOPYRIMIDINE DIONE AND PREPARING METHOD | PFIZER (US) | 1991-12-04 | — | — | CN | disclosed |
| EP-0260817-B1 | QUINAZOLINEDIONES AND PYRIDOPYRIMIDINEDIONES | PFIZER INC. (US) | 1991-05-15 | — | — | EP | disclosed |
| US-4880810-A | Quinazolinediones and pyridopyrimidinediones | PFIZER INC. (US) | 1989-11-14 | — | — | US | disclosed |
| US-4880810-A | Quinazolinediones and pyridopyrimidinediones | PFIZER INC. (US) | 1989-11-14 | — | — | US | disclosed |
| US-4797403-A | Quinazolinediones and pyridopyrimidinediones | PFIZER INC. (US) | 1989-01-10 | — | — | US | disclosed |
| US-4797403-A | Quinazolinediones and pyridopyrimidinediones | PFIZER INC. (US) | 1989-01-10 | — | — | US | disclosed |
| EP-0260817-A1 | Quinazolinediones and pyridopyrimidinediones | PFIZER INC. (US) | 1988-03-23 | — | — | EP | disclosed |
| US-4551458-A | 1-HALOALKYLTHIO DERIVATIVES | MAKHTESHIM CHEMICAL WORKS, LTD. (IL) | 1985-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10249831-B2 | Electronic device containing cyclic lactams | OXA1L, UROD, MRPL21 | MAT2A 4059/4885L3MBTL1 3138/4885KDM4E 2116/4885 |
| US-20180040832-A1 | ELECTRONIC DEVICE CONTAINING CYCLIC LACTAMS | OXA1L, UROD, MRPL21 | MAT2A 4059/4885L3MBTL1 3138/4885KDM4E 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.