Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.37 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.37 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.37 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.37 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17876373 | 0.82 | PTPN1 (0.45) | ALOX15PTPN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11562450 | 0.82 | PTPN1 (0.45) | ALOX15PTPN1ALDH1A1KDM4EHPGD | |
| SCHEMBL8404362 | 0.81 | ALDH1A1 (0.53) | ALOX15PTPN1ALDH1A1KDM4EHPGD | |
| SCHEMBL31292056 | 0.79 | PTPN1 (0.77) | ALOX15PTPN1ALDH1A1KDM4EPOLB | |
| SCHEMBL4044019 | 0.79 | PTPN1 (0.77) | ALOX15PTPN1ALDH1A1KDM4EPOLB | |
| SCHEMBL5013425 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRMAPTRAB9AUSP2 | |
| SCHEMBL7600910 | 0.78 | MAPT (0.50) | ALOX15ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11510460 | 0.77 | MAOB (0.56) | ALOX15PTPN1ALDH1A1TSHRUSP2 | |
| SCHEMBL11397717 | 0.77 | ALOX12 (0.45) | ALOX15PTPN1ALDH1A1KDM4EHPGD | |
| SCHEMBL13978666 | 0.77 | ALDH1A1 (0.58) | ALOX15PTPN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573921-B2 | Substituted N, N-dimethylaminoalkyl ethers of isoflavanone oximes as H1-receptor antagonists | POLFARMEX S.A. (PL) | 2017-02-21 | — | — | US | disclosed |
| US-20160237055-A1 | NOVEL SUBSTITUTED N, N-DIMETHYLAMINOALKYL ETHERS OF ISOFLAVANONE OXIMES AS H1-RECEPTOR ANTAGONISTS | POLFARMEX S.A. (PL) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237055-A1 | NOVEL SUBSTITUTED N, N-DIMETHYLAMINOALKYL ETHERS OF ISOFLAVANONE OXIMES AS H1-RECEPTOR ANTAGONISTS | HRH4, HRH1, HRH3 | ALOX15 722/4885PTPN1 1873/4885ALDH1A1 2014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.