Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914825 | 0.86 | PTPN1 (0.63) | PTPN1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL18021729 | 0.82 | ALOX15 (0.49) | PTPN1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL17876375 | 0.78 | MAPT (0.47) | ALOX15ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL27700653 | 0.78 | ALDH1A1 (0.55) | ALDH1A1HPGDMAPTRAB9AUSP2 | |
| SCHEMBL11562450 | 0.77 | PTPN1 (0.45) | PTPN1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL16446088 | 0.77 | ALOX12 (0.54) | PTPN1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL16445878 | 0.77 | NPC1 (0.49) | PTPN1ALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL31292056 | 0.74 | PTPN1 (0.77) | PTPN1ALOX15ALDH1A1KDM4EKMT2A | |
| SCHEMBL17876359 | 0.74 | ALDH2 (0.39) | PTPN1ALOX15ALDH1A1KDM4EHPGD | |
| SCHEMBL4044019 | 0.74 | PTPN1 (0.77) | PTPN1ALOX15ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406075-A | Silicon-containing polycyclic chromone skeleton compound, preparation method and application thereof | 遵义医科大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-118255735-A | Preparation method of cyclopenta [ b ] chromone compound | 遵义医科大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-114560838-B | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-112898256-B | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-113149948-B | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-111732567-B | Chromone framework-containing polycyclic compound, and preparation method and application thereof | 遵义医科大学 | 2022-07-08 | — | — | CN | disclosed |
| CN-114560838-A | Preparation method of 2-amino-3-formyl chromone compound | 遵义医科大学 | 2022-05-31 | — | — | CN | disclosed |
| CN-113149948-A | Preparation method and application of 3-methylene cyclopentano [ b ] chromone compound | 遵义医科大学 | 2021-07-23 | — | — | CN | disclosed |
| CN-112898256-A | Preparation method of 1, 2-dihydrocyclopenta [ b ] chromene-3, 9-diketone compound | 遵义医科大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-111732567-A | Chromone framework-containing polycyclic compound, and preparation method and application thereof | 遵义医科大学 | 2020-10-02 | — | — | CN | disclosed |
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | VAT1, NQO1, VARS1 | PTPN1 4828/4885ALOX15 503/4885ALDH1A1 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.