SCHEMBL18021771

SCHEMBL18021771

c1ccc(-c2ccc(N(c3ccc4c5c(cccc35)Oc3ccccc3-4)c3cccc4c3oc3ccccc34)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30
GGPS1 O95749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18021780 0.94 KDM4E (0.38) ALOX5KDM4EMAPK1ATM
SCHEMBL16282174 0.93 ALOX5 (0.34) ALOX5
SCHEMBL24126558 0.92 ALOX5 (0.35) ALOX5GGPS1
SCHEMBL18021773 0.92 ALOX5 (0.36) ALOX5KDM4EMAPK1ATMCDC14B
SCHEMBL17999967 0.92 ALOX5 (0.34) ALOX5
SCHEMBL25915583 0.91 ALOX5 (0.35) ALOX5
SCHEMBL24126545 0.91 ALOX5 (0.35) ALOX5
SCHEMBL20724989 0.91 ALOX5 (0.32) ALOX5
SCHEMBL24126119 0.91 ALOX5 (0.36) ALOX5GGPS1
SCHEMBL16282171 0.91 ALOX5 (0.34) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10205103-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-02-12 US disclosed
US-20160240790-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-18 US disclosed
US-20160240790-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-08-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160240790-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CRY2 ALOX5 2075/4885KDM4E 3764/4885MAPK1 1881/4885
US-10205103-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CCNE2, CRY2 ALOX5 2075/4885KDM4E 3764/4885MAPK1 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.