SCHEMBL1802246

SCHEMBL1802246

CCN1CC(NC(=O)c2cc(Cl)c(N)cc2OC)CC1CO

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR4 Q13639 7/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29424266 1.00 HTR4 (0.65) HTR4
SCHEMBL678433 1.00 HTR4 (0.65) HTR4
SCHEMBL29889091 1.00 HTR4 (0.65) HTR4
Hydrochloric Acid SCHEMBL7309004 0.99 HTR4 (0.64) HTR4
SCHEMBL4543915 0.91 HTR4 (0.67) HTR4
Dazopride SCHEMBL184075 0.83 HTR4 (0.72) HTR4
Dazopride SCHEMBL7339808 0.82 HTR4 (0.71) HTR4
SCHEMBL5077815 0.82 DRD2 (0.43) HTR4
SCHEMBL2522742 0.81 DRD4 (0.58) HTR4
Hydrochloric Acid SCHEMBL7309340 0.81 DRD4 (0.57) HTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5229942-A None JP disclosed
US-20230277523-A1 METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2023-09-07 US disclosed
WO-2012170599-A1 NEUROGENESIS BY MUSCARINIC RECEPTOR MODULATION BRAINCELLS, INC. (US) 2012-12-13 WO disclosed
WO-2011091033-A1 MODULATION OF NEUROGENESIS BY PPAR AGENTS BRAINCELLS, INC. (US) 2011-07-28 WO disclosed
WO-2011063115-A1 COMBINATION OF NOOTROPIC AGENT WITH ONE OR MORE NEUROGENIC OR NEUROGENIC SENSITIZING AGENTS FOR STIMULATING OR INCREASING NEUROGENESIS BRAINCELLS INC. (US) 2011-05-26 WO disclosed
WO-2010099217-A1 MODULATION OF NEUROGENESIS USING D-CYCLOSERINE COMBINATIONS BRAINCELLS, INC. (US) 2010-09-02 WO disclosed
EP-2125017-A2 MODULATION OF NEUROGENESIS WITH USE OF MODAFINIL Braincells, Inc. (US) 2009-12-02 EP disclosed
EP-2076288-A2 COMBINATION COMPRISING AN HMG-COA REDUCTASE INHIBITOR AND A SECOND NEUROGENIC AGENT FOR TREATING A NERVOUS SYSTEM DISORDER AND INCREASING NEUROGENESIS Braincells, Inc. (US) 2009-07-08 EP disclosed
EP-2068872-A1 COMBINATIONS CONTAINING A 4-ACYLAMINOPYRIDINE DERIVATIVE Braincells, Inc. (US) 2009-06-17 EP disclosed
EP-2026813-A2 5 HT RECEPTOR MEDIATED NEUROGENESIS Braincells, Inc. (US) 2009-02-25 EP disclosed
WO-2007134136-A2 NEUROGENESIS BY MODULATING ANGIOTENSIN BRAINCELLS, INC. (US) 2007-11-22 WO disclosed
WO-2007134077-A2 5 HT RECEPTOR MEDIATED NEUROGENESIS BRAINCELLS, INC. (US) 2007-11-22 WO disclosed
WO-2007104035-A1 MODULATION OF NEUROGENESIS BY NOOTROPIC AGENTS BRAINCELLS, INC. (US) 2007-09-13 WO disclosed
WO-2007053596-A1 GABA RECEPTOR MEDIATED MODULATION OF NEUROGENESIS BRAINCELLS, INC. (US) 2007-05-10 WO disclosed
WO-2007047978-A2 MODULATION OF NEUROGENESIS BY PDE INHIBITION BRAINCELLS, INC. (US) 2007-04-26 WO disclosed
WO-2007030697-A2 MODULATION OF NEUROGENESIS BY HDAC INHIBITION BRAINCELLS, INC. (US) 2007-03-15 WO disclosed
WO-2007025177-A2 NEUROGENESIS BY MUSCARINIC RECEPTOR MODULATION BRAINCELLS, INC. (US) 2007-03-01 WO disclosed
WO-2002036113-A1 COMPOSITION COMPRISING: SEROTONIN RECEPTOR ANTAGONISTS (5HT-2, 5HT-3) AND AGONIST (5HT-4) RESPIRATORIUS AB (SE) 2002-05-10 WO disclosed
WO-2001095902-A9 A COMPOSITION COMPRISING A COMBINATION OF RECEPTOR AGONISTS AND ANTAGONISTS 2002-04-25 WO disclosed
JP-H05229942-A IMPROVER FOR KINETIC FUNCTION OF DIGESTIVE TRACT TEIKOKU CHEM IND CORP LTD 1993-09-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230277523-A1 METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC34A3, SLC34A2, SLC34A1 HTR4 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.