Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16442797 | 0.93 | FFAR1 (0.39) | NTRK1IGF1RFGFR1NTRK2PPARG | |
| SCHEMBL18021052 | 0.91 | SLC22A12 (0.39) | NTRK1IGF1RFGFR1NTRK2PPARG | |
| SCHEMBL16205959 | 0.87 | MRGPRX4 (0.36) | HCRTR1HCRTR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL19772473 | 0.86 | ALDH1A1 (0.38) | MAPTLMNASMN1; SMN2 | |
| SCHEMBL17796266 | 0.85 | SMN1; SMN2 (0.36) | KMT2AMEN1ARSMN1; SMN2 | |
| SCHEMBL16206142 | 0.84 | PTGER1 (0.39) | MAPT | |
| SCHEMBL16920777 | 0.84 | NQO2 (0.34) | BRD4MAPTLMNASMN1; SMN2 | |
| SCHEMBL16442868 | 0.83 | FFAR1 (0.41) | NTRK1IGF1RFGFR1NTRK2PPARG | |
| SCHEMBL16442860 | 0.83 | KMT2A (0.38) | PPARGKMT2AMEN1MAPTLMNA | |
| SCHEMBL17808629 | 0.83 | LMNA (0.35) | PPARGKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9635857-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-02 | — | — | US | disclosed |
| EP-3061756-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-20160235065-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235065-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | MRPS17, TAOK1, TAOK3 | NTRK1 2080/4885IGF1R 1055/4885FGFR1 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.